European Journal of Chemistry

Stereoselective total synthesis of pectinolide H and 4'-epi-pectinolide H



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Ramesh Perla
Nitin Wasantrao Fadnavis

Abstract

The total synthesis of pectinolide H and 4'-epi-pectinolide H was accomplished with 27% yield in nine steps from inexpensive and commercially available compound, (+)-diethyl tartrate ((+)DET)) by employing swern oxidation, Wittig olefination, Grignard and lactonization reactions.


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Perla, R.; Fadnavis, N. W. Stereoselective Total Synthesis of Pectinolide H and 4’-Epi-Pectinolide H. Eur. J. Chem. 2015, 6, 93-97.

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