European Journal of Chemistry

Application of a multi-component cyclocondensation to develop a bioactive molecular scaffold

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Published: Mar 31, 2016
DOI: https://doi.org/10.5155/eurjchem.7.1.135-136.1360
Keywords:
CNS, 5-HT6, Antagonist, Benzazepine, Furanoquinoline, Cyclocondensation
Section
Short Communication
Issue
Vol. 7 No. 1 (2016): March 2016
Dates
Received 2015-11-09
Accepted 2015-12-05
Published 2016-03-31


Main Article Content

Sankar Chatterjee
Cephalon, Inc., 145 Brandywine Parkway, West Chester, PA 19380-4245, USA

Abstract

A molecular scaffold containing a furanoquinoline motif that offered a unique molecular architecture for 5-hydroxytryptamine 6 receptor antagonism was generated by a multi-component cyclization reaction.


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Chatterjee, S. Application of a Multi-Component Cyclocondensation to Develop a Bioactive Molecular Scaffold. Eur. J. Chem. 2016, 7, 135-136.

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