European Journal of Chemistry 2011, 2(3), 404-409. doi:10.5155/eurjchem.2.3.404-409.267

Synthesis of novel quinazolinone and fused quinazolinones


Mahmoud Refaee Mahmoud (1) , Manal Mohamed El-Shahawi (2) , Fatma Saber Mohamed Abu El-Azm (3,*)

(1) Chemistry Department, Faculty of Science, Ain Shams University, Abbassia 11566, Cairo, Egypt
(2) Chemistry Department, Faculty of Science, Ain Shams University, Abbassia 11566, Cairo, Egypt
(3) Chemistry Department, Faculty of Science, Ain Shams University, Abbassia 11566, Cairo, Egypt
(*) Corresponding Author

Received: 28 Aug 2010, Accepted: 04 Jan 2011, Published: 30 Sep 2011

Abstract


A number of novel quinazolinone derivatives have been synthesized using the readily obtainable 2-[(1Z,3E)-1-benzamido-4-phenyl-1,3-butadien-1-yl]-3,1-benzoxazin-4(H)one (1) via the reaction with different nitrogen nucleophiles such as azines, Schiff’s base, primary aromatic amines, diamines, hydrazine hydrate and hydroxylamine.

2_3_404_409_800


Keywords


Benzoxazinone; Azine; Fused quinazolinones; Nitrogen nucleophiles; Triazinoquinazolinone; Oxadiazinoquinazolinone

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DOI: 10.5155/eurjchem.2.3.404-409.267

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Citations

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[1]. Manal M. Elshahawi, Ahmed K. EL-Ziaty, Jehan M. Morsy, Aly F. Aly
Synthesis and Insecticidal Efficacy of Novel Bis Quinazolinone Derivatives
Journal of Heterocyclic Chemistry  53(5), 1443, 2016
DOI: 10.1002/jhet.2445
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[2]. Mohamed H. Hekal, Fatma S. M. Abu El-Azm
New potential antitumor quinazolinones derived from dynamic 2-undecyl benzoxazinone: Synthesis and cytotoxic evaluation
Synthetic Communications  48(18), 2391, 2018
DOI: 10.1080/00397911.2018.1490433
/


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How to cite


Mahmoud, M.; El-Shahawi, M.; Abu El-Azm, F. Eur. J. Chem. 2011, 2(3), 404-409. doi:10.5155/eurjchem.2.3.404-409.267
Mahmoud, M.; El-Shahawi, M.; Abu El-Azm, F. Synthesis of novel quinazolinone and fused quinazolinones. Eur. J. Chem. 2011, 2(3), 404-409. doi:10.5155/eurjchem.2.3.404-409.267
Mahmoud, M., El-Shahawi, M., & Abu El-Azm, F. (2011). Synthesis of novel quinazolinone and fused quinazolinones. European Journal of Chemistry, 2(3), 404-409. doi:10.5155/eurjchem.2.3.404-409.267
Mahmoud, Mahmoud, Manal Mohamed El-Shahawi, & Fatma Saber Mohamed Abu El-Azm. "Synthesis of novel quinazolinone and fused quinazolinones." European Journal of Chemistry [Online], 2.3 (2011): 404-409. Web. 23 Jan. 2019
Mahmoud, Mahmoud, El-Shahawi, Manal, AND Abu El-Azm, Fatma. "Synthesis of novel quinazolinone and fused quinazolinones" European Journal of Chemistry [Online], Volume 2 Number 3 (30 September 2011)

DOI Link: https://doi.org/10.5155/eurjchem.2.3.404-409.267

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