European Journal of Chemistry 2010, 1(2), 73-75 | doi: https://doi.org/10.5155/eurjchem.1.2.73-75.34 | Get rights and content






  OPEN ACCESS | PEER-REVIEWED | RESEARCH ARTICLE | DOWNLOAD PDF | VIEW FULL-TEXT PDF | TOTAL VIEWS

Synthesis, characterization and crystal structure of 1-(4-methylbenzoyl)-3-(4 aminosulfonylphenyl)thiourea


Aamer Saeed (1,*) , Amara Mumtaz (2) , Ulrich Florke (3)

(1) Department of Chemistry, Quaid-I-Azam University, Islamabad, 45320, Pakistan
(2) Department of Chemistry, Quaid-I-Azam University, Islamabad, 45320, Pakistan
(3) Department Chemie, Fakultät fur Naturwissenschaften, Universitat Paderborn, Warburgerstrasse 100, D-33098, Paderborn, Germany
(*) Corresponding Author

Received: 04 Apr 2010 | Revised: 12 Apr 2010 | Accepted: 09 Apr 2010 | Published: 15 Jun 2010 | Issue Date: June 2010

Abstract


An efficient synthesis of the title compound, 1-(4-methylbenzoyl)-3-(4-aminosulfonyl phenyl)thiourea,  was carried out by reaction of 4-methylbenzoyl chloride with potassium thiocyanate in acetone to afford 4-methylbenzoyl isothiocyanate in situ followed by treatment with sulfanilamide. The structure was confirmed by spectroscopic data and elemental analyses. The molecular structure was determined from single crystal X-ray diffraction data. It crystallizes in the monoclinic space group P21/n with unit cell dimensions of a = 4.8116(9) Å, b = 17.150(3) Å, c = 18.677(3) Å, γ = 96.487(4) °, and V = 1531.4(5) Å3.

1_2_73_75_800



Keywords


Thiourea; Sulfonyl thiourea; Single crystal X-ray diffraction

Full Text:

PDF /    /


DOI: 10.5155/eurjchem.1.2.73-75.34

Links for Article


| | | | | | |

| | | | | | |

Related Articles




Article Metrics

This Abstract was viewed 924 times | PDF Article downloaded 685 times


Citations

/


[1]. Ilkay Gumus, Serpil Gonca, Birdal Arslan, Ebru Keskin, Ummuhan Solmaz, Hakan Arslan
N-(Dibenzylcarbamothioyl)-3-methylbutanamide: Crystal structure, Hirshfeld surfaces and antimicrobial activity
European Journal of Chemistry  8(4), 410, 2017
DOI: 10.5155/eurjchem.8.4.410-416.1650
/


[2]. Gün Binzet, Gülten Kavak, Nevzat Külcü, Süheyla Özbey, Ulrich Flörke, Hakan Arslan
Synthesis and Characterization of Novel Thiourea Derivatives and Their Nickel and Copper Complexes
Journal of Chemistry  2013, 1, 2013
DOI: 10.1155/2013/536562
/


[3]. Sohail Saeed, Naghmana Rashid, Peter Jones, Rizwan Hussain
Thermomechanical studies of thermally stable metal-containing epoxy polymers from diglycidyl ether of bisphenol A and amino-thiourea metal complexes
European Journal of Chemistry  2(1), 77, 2011
DOI: 10.5155/eurjchem.2.1.77-82.183
/


[4]. Gun Binzet, Ulrich Flörke, Nevzat Külcü, Hakan Arslan
Crystal and molecular structure of bis(4-bromo-N-(diethylcarbamothioyl)benzamido)nickel(II) complex
European Journal of Chemistry  3(1), 37, 2012
DOI: 10.5155/eurjchem.3.1.37-39.591
/


[5]. Gun Binzet, Ulrich Flörke, Nevzat Külcü, Hakan Arslan
Crystal and molecular structure of bis(4-bromo-N-(di-n-butylcarbamothioyl)benzamido) copper(II) complex
European Journal of Chemistry  3(2), 211, 2012
DOI: 10.5155/eurjchem.3.2.211-213.594
/


[6]. Gun Binzet, Bülent Zeybek, Esma Kılıç, Nevzat Külcü, Hakan Arslan
Determination of the Ionization Constants of Some Benzoyl Thiourea Derivatives in Dioxane-Water Mixture
Journal of Chemistry  2013, 1, 2013
DOI: 10.1155/2013/201238
/


[7]. Mustafa Karakaya, Yusuf Sert, Mehmet Kürekçi, Buse Eskiyurt, Çağrı Çırak
Theoretical and experimental investigations on vibrational and structural properties of tolazamide
Journal of Molecular Structure  1095, 87, 2015
DOI: 10.1016/j.molstruc.2015.04.028
/


[8]. Sumera Zaib, Aamer Saeed, Karin Stolte, Ulrich Flörke, Mohammad Shahid, Jamshed Iqbal
New aminobenzenesulfonamide–thiourea conjugates: Synthesis and carbonic anhydrase inhibition and docking studies
European Journal of Medicinal Chemistry  78, 140, 2014
DOI: 10.1016/j.ejmech.2014.03.023
/


References

[1]. Koch, K.R. Coord. Chem. Rev.2001, 216-217, 473-488
doi:10.1016/S0010-8545(01)00337-X

[2]. Krishnamurthy, R.; Govindaraghavan, S.; Narayanasamy, J. Pesticide Science 1999, 52, 145-151.

[3]. Sijia, X.; Liping, D.; .Shaoyong, C.; Liangbin, J. Chem. J. Internet 2003, 5, 67-70.

[4]. Wang, X-C.; Wang, V.; Quan, Z-J.; Wang, M-G.; Li, Z. J. Chem. Res., 2005, 61, 689-690.

[5]. Saeed, A.; Parvez, M. J. Heterocyl. Chem. 2006, 43, 1027-1030.
doi:10.1002/jhet.5570430431

[6]. Snieckus, V; Chem. Rev. 1990, 90, 879-933
doi:10.1021/cr00104a001

[7]. Bestmann, H.J.; Kern, F.; Schafer, D.; Witschel, M.C. Angew. Chem. Int. Ed. Engl. 1992 31, 795-796.
doi:10.1002/anie.199207951

[8]. Stokstad, E. L. R.; Jãoekes, T. H. J. Nutr. 1987, 117; 1335-1341.

[9]. Botet, J.; Mateos, L.; Revuelta, J. L; Santos, M. A. Eukaryotic Cell, 2007, 2102–2111.
doi:10.1128/EC.00266-07
PMid:17873082    PMCid:2168415

[10]. Saeed, A.; Flörke, U. Acta Cryst. 2006, E62, o2924- o2924.

[11]. Yusof, M. S. M.; Hamid, M. A.; Ramli, R. N. H. R.; Yamin, B. M. Acta Cryst. 2006, E62, o2131- o2131.

[12]. Saeed, A.; Flörke, U. Acta Cryst. 2006, E62, o5036-o5036.

Supporting information


The Supplementary Material for this article can be found online at: Supplementary files

How to cite


Saeed, A.; Mumtaz, A.; Florke, U. Eur. J. Chem. 2010, 1(2), 73-75. doi:10.5155/eurjchem.1.2.73-75.34
Saeed, A.; Mumtaz, A.; Florke, U. Synthesis, characterization and crystal structure of 1-(4-methylbenzoyl)-3-(4 aminosulfonylphenyl)thiourea. Eur. J. Chem. 2010, 1(2), 73-75. doi:10.5155/eurjchem.1.2.73-75.34
Saeed, A., Mumtaz, A., & Florke, U. (2010). Synthesis, characterization and crystal structure of 1-(4-methylbenzoyl)-3-(4 aminosulfonylphenyl)thiourea. European Journal of Chemistry, 1(2), 73-75. doi:10.5155/eurjchem.1.2.73-75.34
Saeed, Aamer, Amara Mumtaz, & Ulrich Florke. "Synthesis, characterization and crystal structure of 1-(4-methylbenzoyl)-3-(4 aminosulfonylphenyl)thiourea." European Journal of Chemistry [Online], 1.2 (2010): 73-75. Web. 30 May. 2020
Saeed, Aamer, Mumtaz, Amara, AND Florke, Ulrich. "Synthesis, characterization and crystal structure of 1-(4-methylbenzoyl)-3-(4 aminosulfonylphenyl)thiourea" European Journal of Chemistry [Online], Volume 1 Number 2 (15 June 2010)

The other citation formats (EndNote | Reference Manager | ProCite | BibTeX | RefWorks) for this article can be found online at: How to cite item


DOI Link: https://doi.org/10.5155/eurjchem.1.2.73-75.34

| | | | | | |

| | | | | |

Save to Zotero Save to Mendeley



European Journal of Chemistry 2010, 1(2), 73-75 | doi: https://doi.org/10.5155/eurjchem.1.2.73-75.34 | Get rights and content

Refbacks

  • There are currently no refbacks.




Copyright (c)




© Copyright 2010 - 2020  Atlanta Publishing House LLC All Right Reserved.

The opinions expressed in all articles published in European Journal of Chemistry are those of the specific author(s), and do not necessarily reflect the views of Atlanta Publishing House LLC, or European Journal of Chemistry, or any of its employees.

Copyright 2010-2020 Atlanta Publishing House LLC. All rights reserved. This site is owned and operated by Atlanta Publishing House LLC whose registered office is 2850 Smith Ridge Trce Peachtree Cor GA 30071-2636, USA. Registered in USA.

hatay escort hatay escort corlu escort corum escort burgaz escort giresun escort aydin escort ordu escort erzincan escort hatay escort sivas escort rize escort edirne escort aksaray escort kibris escort isparta escort erzurum escort tekirdag escort usak escort urfa escort kastamonu escort kibris escort manisa escort giresun escort urfa escort nevsehir escort sivas escort yalova escort ordu escort hatay escort yalova escort amasya escort kayseri escort ordu escort maras escort canakkale escort yalova escort balikesir escort manisa escort urfa escort mugla escort trabzon escort bolu escort corlu escort diyarbakir escort isparta escort kutahya escort elazig escort erzurum escort sakarya escort afyon escort kutahya escort konya escort agri escort cesme escort sinop escort sivas escort konya escort kibris escort adapazari escort luleburgaz escort adana escort kibris escort rize escort sakarya escort alanya escort isparta escort burdur escort konya escort bitlis escort canakkale escort sivas escort amasya escort mus escort aydin escort van escort yalova escort kastamonu escort mardin escort bolu escort afyon escort sakarya escort isparta escort tokat escort trakya escort bayburt escort urfa escort mardin escort