The fate of leachate of pharmaceuticals like amoxicillin, ibuprofen and caffeine in the soil using soil columns

Shehdeh Jodeh, Halimeh Staiti, Marwan Haddad, Tamara Renno, Abdelnaser Zaid, Nidal Jaradat, Maher Kharoaf

Abstract


From an environmental engineering point of view, pharmaceuticals such as antibiotics are a group of man-made chemicals of concern entering the environment in concentrations at which, the health effects are unknown. The problem that may be created by the presence of antibiotics at low concentrations in the environment is the development of antibiotic resistant microorganisms. In this study, three pharmaceutical drugs manufactured in Palestine were studied in waste water and their adsorption in agriculture soil was studied using soil columns. During the study of soil columns, it was noted that the concentration of caffeine in leachate was higher than that of ibuprofen and amoxicillin, as caffeine has higher aqueous solubility. Ibuprofen and amoxicillin were present in leachate with very small concentrations, due to their degradation and decomposition into other substances that may be harmful, and affect the natural properties of soil, groundwater and human health. The decomposition percentages of the pharmaceuticals in the soil columns were 97.82, 97.88 and 86.52% for amoxicillin, ibuprofen and caffeine for one year’s study, respectively. For the fifteen years, the decomposition percentages were 94.04, 96.60 and 93.70% for amoxicillin, ibuprofen and caffeine, respectively.

3_4_480_484_800


Keyword(s)


Kinetics; Leachate; Adsorption; Pharmaceuticals; Chemical oxygen demand (COD); Biochemical oxygen demand (BOD)

European Journal of Chemistry, 3 (4), (2012), 480-484

Full Text:

PDF    /    /

DOI: http://dx.doi.org/10.5155/eurjchem.3.4.480-484.698

 

Cited-By

[1]. The study of kinetics and thermodynamics of selected pharmaceuticals and personal care products on agriculture soil
Shehdeh Jodeh
European Journal of Chemistry  Volume: 3  Issue: 4  First page: 468  Year: 2012  
/

[2]. Synthesis, characterization and comparative study the antibacterial activities of some imine-amoxicillin derivatives
Ivan Hameed Rouil Tomi, Amer Hasan Abdullah, Ali Hussein Raheemah Al-Daraji, Selma Abdul Rudha Abbass
European Journal of Chemistry  Volume: 4  Issue: 2  First page: 153  Year: 2013  
/

 


References

[1]. Stegmann, R.; Christensen, T. H.; Cossu, R. Landfill leachate: an introduction, in: Landfilling of Waste: Leachate, pp. 3-14, Elsevier Applied Science, London and New York, 1992.

[2]. Bjerg, P. L.; Rugge, K.; Pedersen, J.; Christensen, T. H. Environ. Sci. Technol. 1995, 29, 1387-1394.
http://dx.doi.org/10.1021/es00005a035
PMid:22192037

[3]. Hernando, M. D.; Mezcua, M.; Fernandez-Alba, A. R.; Barcelo, D. Talanta 2006, 69, 334-342.
http://dx.doi.org/10.1016/j.talanta.2005.09.037
PMid:18970571

[4]. Pico, Y.; Andreu, V. Anal. Bioanal. Chem. 2007, 387, 1287-1299.
http://dx.doi.org/10.1007/s00216-006-0843-1
PMid:17082879

[5]. Okuda, T.; Yamashita, N.; Tanaka, H.; Matsukawa, K.; Tanabe, A. Environ. Int. 2009, 35, 815-820.
http://dx.doi.org/10.1016/j.envint.2009.01.006
PMid:19201472

[6]. Schroder, H. F. Waste Manage. 1999, 19, 111-123.
http://dx.doi.org/10.1016/S0956-053X(99)00002-1

[7]. Toze, S. Agric. Water Manage. 2006, 80, 147-159.
http://dx.doi.org/10.1016/j.agwat.2005.07.010

[8]. Jimenez, B. Int. Rev. Environ. Strategies 2006, 4, 229-250.

[9]. Miller, K. D.; Husmann, H.; Nalik, H. P.; Schomburg, G. Chromatographia 1990, 30, 245-248.
http://dx.doi.org/10.1007/BF02319701

[10]. Heberer, T.; Stan, H. J. Int. J. Environ. Anal. Chem. 1997, 67, 113-124.
http://dx.doi.org/10.1080/03067319708031398

[11]. Heberer, T.; Dunnbier, U.; Reilich, C.; Stan, H. J. Fresenius. Environ. Bull. 1997, 6, 438-443.

[12]. Nason, J. A. "Literature Review: Occurrence and Fate of Pharmaceutical Compounds in Landfill Leachate" Prepared for: Oregon Association of Clean Water Agencies, EPA Publisher, Washington D. C., U.S.A, 2007.

[13]. Kolpin, D. W.; Furlong, E. T.; Meyer, M. T.; Thurman, E. M.; Zaugg, S. D.; Barber. L. B. Environ. Sci. Technol. 2002, 36, 1202-1211.
http://dx.doi.org/10.1021/es011055j

[14]. Cordy, G. E.; Duran, N. L.; Bouwer, H.; Rice, R. C.; Furlong, E. T.; Zaugg, S. D.; Meyer, M. T.; Barber, L. B.; Kolpin, D. W. Ground Water Monit. R. 2004, 24, 58-69.
http://dx.doi.org/10.1111/j.1745-6592.2004.tb00713.x

[15]. Andrew, D. E.; Lenore, S. C.; Arnold, E. G. Standard methods for the examination of water and wastewater, 19th edition., American Public Health Association Publisher, Waldorf, Maryland, U.S.A, 1995

[16]. Anyakora, C. H.; Nwaeze, K.; Awodele, O.; Nwadike, C.; Arbabi, M.; Coker, H. J. Chem. Environ Ecotoxicol. 2011, 3, 25-31.

[17]. Dwivedia, A.; Dhar, G. K.; Rajeev, J. Chem. Eng. J. 2011, 168, 1279-1288.
http://dx.doi.org/10.1016/j.cej.2011.02.041

[18]. Tang, K.; Cai, J.; Zhang, P. Ind. Eng. Chem. Res. 2011, 56, 964-971.

[19]. Navarro, P. G.; El Bekkouri, A.; Reinoso, E. R. Analyst. 1998, 123, 2263-2266.
http://dx.doi.org/10.1039/a804577a

[20]. Baek, M.; Ijagbemi, C. O.; Se-Jin, O.; Kim, D. J. Hazard. Mater. 2010, 176, 820-828.
http://dx.doi.org/10.1016/j.jhazmat.2009.11.110
PMid:20036052

[21]. Le-Minh, N.; Khan, S. J.; Drewes, J. E.; Stuetz, R. M. Fate of antibiotics during municipal water recycling treatment processes, UNSW Water Research Center, School of Civil and Environmental Engineering, University of New South Wales, volume 44, Australia, 2010.
PMid:20619433

[22]. Lim, L.; Go, M. Eur. J. Pharm. Sci. 2000, 10, 17-28.
http://dx.doi.org/10.1016/S0928-0987(99)00084-6

[23]. Caviglioli, G.; Valeria, P.; Brunella, P.; Sergio, C.; Attilia, A.; Gaetano, A. J. Pharm. Biomed. Anal. 2002, 30, 377-896.
http://dx.doi.org/10.1016/S0731-7085(02)00400-4

[24]. Jacobs, L. E.; Fimmen, R. L.; Chin Y. Water 2011, 45, 4449-4458.
http://dx.doi.org/10.1016/j.watres.2011.05.041
PMid:21714984

[25]. Sathyanarayana, N. G.; Bhavya, B.; Nandhini, A. J. Ind. Microbiol. Biotechnol. 2012, 93, 545-554.
http://dx.doi.org/10.1007/s00253-011-3737-x
PMid:22139018

[26]. Kakimoto, T.; Funamiz, N. Chemosphere 2007, 66, 2219-2224.
http://dx.doi.org/10.1016/j.chemosphere.2006.09.060
PMid:17109929


Refbacks

  • There are currently no refbacks.