European Journal of Chemistry

Convenient synthesis of some new pyrazolo[5,1-c]triazines, isoxazolo[3,4-d] pyrimidine and pyridine derivatives containing benzofuran moiety



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Abdou Osman Abdelhamid
Abdelgawad Ali Fahmi
Amna Ali Mohamed Alsheflo

Abstract

Pyrazolo[5,1-c][1,2,4]triazine, [1,2,4]triazolo[3,4-c][1,2,4]triazine, benzo[4,5]-imidazo[2,1-c][1,2,4]triazine, isoxazole, isoxazolo[3,4-d]pyridazine, pyrazole, pyridine, substituted urea and phenyl carbamate derivatives containing benzofuran moiety were synthesized via reaction of sodium salt of 5-hydroxy-l-benzofuran-2-ylpropenone or 1-(benzofuran-2-yl)-3-(dimethylamino)prop-2-en-1-one with diazotized heterocyclic amines, hydroximoyl chlorides and active methylene compounds. The structures of all the newly synthesized compounds were confirmed by elemental analyses, spectral data, and alternative synthetic routes, whenever possible.

3_2_129_137_800


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Abdelhamid, A. O.; Fahmi, A. A.; Alsheflo, A. A. M. Convenient Synthesis of Some New pyrazolo[5,1-c]triazines, isoxazolo[3,4-D] Pyrimidine and Pyridine Derivatives Containing Benzofuran Moiety. Eur. J. Chem. 2012, 3, 129-137.

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References

[1]. Rao, D. R.; Raychaudhuri, S. P.; Verma, V. S. Int. J. Tropical Plant Dis. 1994, 12, 177-185.

[2]. Hinshaw, B. C; Lconoudakis, O.; Townsend, L. B. Abstracts 112d National Meeting of the American Chemical Society, D. C. Washington. Sept. No MEDI-15, 1971.

[3]. Ito, I. Japanese Patent 70301011971; Chem. Abstr. 1974, 22827, 1971.

[4]. Tseng, C. P. U. S. Pat. 1989, 4838925; Chem. Abstr. 1990, 112, 7508.

[5]. Sakane, K.; Kawabata, K.; Inamoto, Y. Eur. Pat. 1989, 332156; Chem. Abstr. 1990, 112, 216538.

[6]. Fujikawa, Y.; Suzuki, M.; Sakashita, M.; Tanaka, S.; Wakamatsu, M.; Miyasaka, S. Jpn. Kokai Tokkyo Koho JP 01, 221, 381 [89, 221, 381] (CI. C07D487/04) 1989; Chem. Abstr. 1990, 112, 158268j.

[7]. Tseng, S. S.; Brabander, J. H.; Epstein, W. J. U. S. Pat. 1990, 4963553; Chem. Abstr. 1991, 114, 228937.

[8]. Taylor, R. C.; Stauffer, F. H.; Tomezuk, B. E. U. S. Pat. 1992, 5114944; Chem. Abstr. 1992, 117, 90318.

[9]. Hibino, H.; Myamoto, Y.; Myajima, M.; Maeda, H. Jpn. Kokai Tokkyo Koho Jp 05, 213, 756 [93, 213, 756] (CI. A61K31/505); Chem. Abstr. 1993, 119, 256547p.

[10]. Allen, E. E.; Maccoss, M.; Chakravarty, P. K.; Patchett, A. A.; Greenlee, W. J.; Walsh, T. F. Eur. Pat. 1992, 490587; Chem. Abstr. 1992, 117, 151008.

[11]. Gatta, F.; Perotti, F.; Gradoni, L.; Gramiccia, M.; Orsini, S.; Palazzo, G.; Rossi, V. Eur. J. Med. Chem. 1990, 25, 419-424.
http://dx.doi.org/10.1016/0223-5234(90)90005-N

[12]. Ahmed, A. H.; Hozayen, W. H.; El-Gandour, A. H. H; Abdelhamid, A. O. J. Heterocycl. Chem. 2007, 44, 803-810.
http://dx.doi.org/10.1002/jhet.5570440408

[13]. Abdelhamid, A. O.; Sayed, A. R.; Zaki, Y. H. Phosphorus Sulfur Silicon Relat. Elem. 2007, 182, 1447-1457.
http://dx.doi.org/10.1080/10426500701242145

[14]. Abdelhamid, A. O.; Abdelaziz, H. M. Phosphorus Sulfur Silicon Relat. Elem. 2007, 182, 2791-2800.
http://dx.doi.org/10.1080/10426500701521548

[15]. Abdelhamid, A. O.; El-Ghandour, A. H.; El-Reedy, A. A. M. J. Chin. Chem. Soc. 2008, 55, 406-413.

[16]. Abdelhamid, A. O.; Fahmi, A. A.; Halim, K. N. M. Eur. J. Chem. 2011, 2(3), 317-323.
http://dx.doi.org/10.5155/eurjchem.2.3.317-323.420

[17]. Keshk, E. M. Heteroatom Chem. 2004, 15, 85-91.
http://dx.doi.org/10.1002/hc.10219

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