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Synthesis of some novel pyridine and naphthyridine derivatives Abdelrazek, Fathy Mohamed Kassab, Nazmi Abdel-Latif Metwally, Nadia Hanafy Sobhy, Nehal Ahmed Fur-2-ylethylidenemalononitrile Thien-2-ylethylidenemalononitrile Dihydro-pyridines Pyrazolo-naphthyridines Pyrimido-naphthyridines 2-[1-(Furan- or thiophen-2-yl)ethylidene)malononitriles (1a,b) undergo dimerization reactions in ethanol catalyzed by sodium ethoxide to afford 2-[4,6-di(furan- or thiophen-2-yl)-3-cyano-6-methyl-5,6-dihydropyridin-2(1H)-ylidene]malononitrile derivatives (2a,b), respectively. Compounds 2a and 2b couple with arene diazonium salts (3a-c) to afford the hydrazo derivatives (4a-f). They react also with hydrazines (5a,b) to afford the pyrazolo[3,4-H][1,6]naphthyridine derivatives (6a-d) and with urea derivatives (7a-c) to afford the pyrimido[4,5-H][1,6]naphthyridine derivatives (8a-f), respectively. Atlanta Publishing House LLC 2010-12-22 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://www.eurjchem.com/index.php/eurjchem/article/view/104 10.5155/eurjchem.1.4.368-372.104 European Journal of Chemistry; Vol. 1 No. 4 (2010): December 2010; 368-372 2153-2257 2153-2249 eng https://www.eurjchem.com/index.php/eurjchem/article/view/104/PDF