2026-05-07T07:38:26Z https://www.eurjchem.com/index.php/eurjchem/oai

oai:ojs.www.eurjchem.com:article/1070 2014-09-30T03:41:50Z eurjchem:ART driver

Chemical constituents and cytotoxic activities of the extracts of Melilotus indicus Ahmed, Sayed Abdel Kader Al-Refai, Mahmoud Fabaceae Phenolics Flavonoids Melilotus indicus Cytotoxic activity Phytochemical studies The phytochemical investigation of the ethanolic extract of the aerial parts of Melilotus indicus resulted in the isolation of eight known flavonoids, namely; catechin (1), epicatechin (2), taxifolin (3), quercetin (4), quercetin 3-O-β-D-glucopyranoside (5), and quercetin 3-O-α-L-rhamnopyranoside (6), isorhamnetin 3-O-β-D-glucopyranoside (7) and isorhamnetin 3-O-β-D-rutinoside (8). These compounds have never been isolated from this species. The cytotoxic activities of the extracts of Melilotus indicus was evaluated by MTT assay against six cancer cell lines using doxorubicin as standard drug. The chloroform extract was the most potent cytotoxic agent against HepG-2cells with an IC50: 9.21 µg/mL. Atlanta Publishing House LLC 2014-09-30 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://www.eurjchem.com/index.php/eurjchem/article/view/1070 10.5155/eurjchem.5.3.503-506.1070 European Journal of Chemistry; Vol. 5 No. 3 (2014): September 2014; 503-506 2153-2257 2153-2249 eng https://www.eurjchem.com/index.php/eurjchem/article/view/1070/pdf_1070