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oai:ojs.www.eurjchem.com:article/1251 2015-06-30T08:25:37Z eurjchem:ART driver

Pyridazine and its related compounds: Part 32. Synthesis and antimicrobial evaluation of some 3-substituted amino-4,5,6-triphenylpyridazine derivatives Deeb, Ali Abdel Hamid El-Mariah, Fatma Abdel Rahman El-Mawgoud, Heba Kamal Abd 3-Aminopyridazin Anti-microbial activity Benzil monohydrazone Pyridazine sulfonamides Pyrimido[1 2-b]pyridazines 3-Substituted aminopyridazine 3-Amino-4,5,6-triphenylpyridazine was subjected to some selected reactions with nitrous acid, formic acid/dimethylformamide, acetic anhydride, benzoyl chloride, chloroacetyl chloride, acetaldehyde, diethyl malonate, malonic acid/phosphoryl chloride, diethyl oxalate, ethyl cyanoacetate, ethyl acetoacetate, and ethyl benzoylacetate to give new 3-substituted aminopyridazine derivatives. A few sulfonamide derivatives (new) were also prepared. The structures of the synthesized compounds were proved by their infrared, mass spectra, 1H NMR, and elemental analysis. The antimicrobial activity of the compounds obtained was examined against some selected microorganisms. Atlanta Publishing House LLC 2015-06-30 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://www.eurjchem.com/index.php/eurjchem/article/view/1251 10.5155/eurjchem.6.2.211-218.1251 European Journal of Chemistry; Vol. 6 No. 2 (2015): June 2015; 211-218 2153-2257 2153-2249 eng https://www.eurjchem.com/index.php/eurjchem/article/view/1251/pdf_1251