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oai:ojs.www.eurjchem.com:article/1310 2015-12-31T11:02:45Z eurjchem:ART driver

Synthesis, characterization and antimicrobial studies of imine derivatives of amoxicillin Islam, Muhammad Shafiq, Zahid Hussain, Mazhar Ahmad, Hafiz Badaruddin Hussain, Muhammad Ajaz Antibiotics Amoxicillin Schiff’s base Condensation Imine derivatives Antimicrobial activity Some novel imine derivatives (1-14) of a broad spectrum antibiotic amoxicillin were prepared by condensation with different carbonyl compounds. The amoxicillin imine derivatives were characterized using elemental analysis and spectroscopic techniques such as FT-IR and 1H NMR. The prepared imine derivatives were evaluated for antimicrobial activities against some pathogens using disc diffusion method. The results of present studies demonstrate enhanced antimicrobial activity of the novel imine derivatives of amoxicillin as compared to the parent drug. Atlanta Publishing House LLC 2015-12-31 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://www.eurjchem.com/index.php/eurjchem/article/view/1310 10.5155/eurjchem.6.4.417-421.1310 European Journal of Chemistry; Vol. 6 No. 4 (2015): December 2015; 417-421 2153-2257 2153-2249 eng https://www.eurjchem.com/index.php/eurjchem/article/view/1310/pdf_1310