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oai:ojs.www.eurjchem.com:article/1447 2016-09-30T03:57:42Z eurjchem:ART driver

Utility of β-diketones in heterocyclic synthesis: Synthesis of new tetrahydro-pyrimidinethione, pyrazole, thiophene, dihydropyridine, dihydropyrane, pyridazine derivatives and investigation of their antimicrobial activity Reheim, Mohamed Ahmed Mahmoud Abdel Hafiz, Ibrahim Saad Abdel Mohamed, Safaa Pyrazole Thiophene β-Diketones Dihydropyridine Antimicrobial activity Tetrahydropyrimidinethione A series of many important diverse number of fused heterocyclic systems were prepared from the reaction of 1-(2-hydroxynaphthalen-1-yl)-3-phenylpropane-1,3-dione with some bifunctional nucleophiles, these reactions mainly proceed via condensation of 1-(2-hydroxynaphthalen-1-yl)-3-phenylpropane-1,3-dione with the aldehydic function followed by nucleophilic attack. Structures of the new compounds were established by elemental analyses and spectral data. Some of the products were also screened in vitro for their antimicrobial activity. Atlanta Publishing House LLC 2016-09-30 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://www.eurjchem.com/index.php/eurjchem/article/view/1447 10.5155/eurjchem.7.3.298-308.1447 European Journal of Chemistry; Vol. 7 No. 3 (2016): September 2016; 298-308 2153-2257 2153-2249 eng https://www.eurjchem.com/index.php/eurjchem/article/view/1447/pdf_1447