2026-05-25T00:45:50Z https://www.eurjchem.com/index.php/eurjchem/oai

oai:ojs.www.eurjchem.com:article/1537 2017-03-31T07:00:46Z eurjchem:ART driver

Synthesis and antimicrobial activity of 1,3-bis-butyl-5-(4-iodophenyl)-1,3,5-triazacyclohexane Lefrada, Leila Köhn, Randolf Malki, Souhila Mazouz, Wissam Bouchemma, Ahcene Hadjem, Meriem Formalin Synthesis n-Butylamine 4-Iodoaniline Triazacyclohexane Antibacterial activity This work describes the synthesis, structural characterization and antibacterial activities of 1,3,5-triazacyclohexane type of new compound 1,3-bis-butyl-5-(4-iodophenyl)-1,3,5-triazacyclohexane. The new triazacyclohexanes (R3TAC) with mixed aryl and alkyl N-substituents are synthesized by the reaction of a 1:2 mixture of 4-iodoaniline and n-butylamine with formalin. The synthesized compounds were characterized by spectral analysis IR, 1H NMR and 13C NMR. The compound was screened for it’s antibacterial activity against Gram-positive and Gram-negative bacteria by the diffusion method on agar medium. Atlanta Publishing House LLC 2017-03-31 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://www.eurjchem.com/index.php/eurjchem/article/view/1537 10.5155/eurjchem.8.1.82-84.1537 European Journal of Chemistry; Vol. 8 No. 1 (2017): March 2017; 82-84 2153-2257 2153-2249 eng https://www.eurjchem.com/index.php/eurjchem/article/view/1537/pdf_1537