2026-05-10T13:15:29Z https://www.eurjchem.com/index.php/eurjchem/oai

oai:ojs.www.eurjchem.com:article/1563 2017-06-30T04:23:02Z eurjchem:ART driver

Synthesis and antimicrobial activity of some novel N-substituted benzimidazoles Gund, Dnyandev Radhu Tripathi, Alok Pramod Vaidya, Sanjay Dashrath Alkylation Benzoylation Benzimidazole Antifungal activity Antibacterial activity Condensation reaction Synthesis of a series of new substituted benzimidazole derivatives by the condensation of     o-phenylenediamine with urea to give 1,3-dihydro-benzimidazol-2-one which reacted with phosphoryl chloride to give 2-chloro-1H-benzimidazole is reported. The product was then alkylated at the benzimidazole NH with different electrophilic reagents leading to functionalized derivatives. Structures of the newly synthesized products have been deduced on the basis of spectral and analytical data. The synthesized compounds were screened for their antimicrobial activity. This exhibited some promising results towards testing organism in-vitro. Atlanta Publishing House LLC 2017-06-30 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://www.eurjchem.com/index.php/eurjchem/article/view/1563 10.5155/eurjchem.8.2.149-154.1563 European Journal of Chemistry; Vol. 8 No. 2 (2017): June 2017; 149-154 2153-2257 2153-2249 eng https://www.eurjchem.com/index.php/eurjchem/article/view/1563/pdf_1563