2026-05-15T22:45:23Z https://www.eurjchem.com/index.php/eurjchem/oai

oai:ojs.www.eurjchem.com:article/1566 2017-06-30T04:23:02Z eurjchem:ART driver

Correlation analysis of the rates of solvolysis of 4-bromopiperidine: A reaction following a Grob fragmentation pathway Kevill, Dennis Neil Ryu, Zoon Ha D’Souza, Malcolm John Solvolysis Mechanism Correlation 4-Bromopiperidine Grob fragmentation Grunwald-Winstein equation A Grunwald-Winstein treatment of the specific rates of solvolysis of 4-bromopiperidine gives for aqueous ethanol, methanol, acetone, and dioxane a very good logarithmic correlation against the YBr solvent ionizing power values with a slope (m value) of 0.46±0.02, consistent with the operation of a synchronous Grob fragmentation mechanism. When the organic component of the solvent is 2,2,2-trifluoroethanol (TFE), the data points show a negative deviation, consistent with an appreciable deactivating interaction of the acidic TFE component of the solvent with the lone-pair of electrons present on the nitrogen. Atlanta Publishing House LLC 2017-06-30 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://www.eurjchem.com/index.php/eurjchem/article/view/1566 10.5155/eurjchem.8.2.162-167.1566 European Journal of Chemistry; Vol. 8 No. 2 (2017): June 2017; 162-167 2153-2257 2153-2249 eng https://www.eurjchem.com/index.php/eurjchem/article/view/1566/pdf_1566