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oai:ojs.www.eurjchem.com:article/1732 2018-09-30T08:12:27Z eurjchem:ART driver

Eco-friendly and simple synthesis of some non-natural flavones through chalcones Rahman, Mohammad Saidur Alam, Sayeda Shakila Happy, Kamrunnahar Hossain, Mohammad Mamun Islam, Mohammad Khademul Biswas, Foni Bushon Iodine Flavones Chalcones Sulfuric acid Microwave chemistry Conventional synthesis A distinctive feature of polyphenolics is the possession of biological properties such as antioxidant and antimicrobial activities. Simple synthesis and study about such important class of compounds and their analogs are very important to enhance the understanding of their role in human health and diseases. Accordingly, a series of chalcones (2a-f) have been synthesized by Claisen-Schmidt condensation reaction with required acetophenones and aromatic aldehydes in high yields. The conversion of chalcones to the corresponding flavones (1a-g) taking minimal amount of dimethyl sulfoxide with iodine in presence of sulfuric acid was carried out under microwave conditions in high yields. Atlanta Publishing House LLC 2018-09-30 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://www.eurjchem.com/index.php/eurjchem/article/view/1732 10.5155/eurjchem.9.3.236-240.1732 European Journal of Chemistry; Vol. 9 No. 3 (2018): September 2018; 236-240 2153-2257 2153-2249 eng https://www.eurjchem.com/index.php/eurjchem/article/view/1732/pdf_1732 Copyright (c) 2018 Authors