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oai:ojs.www.eurjchem.com:article/1850 2019-12-31T03:23:22Z eurjchem:ART driver

Synthesis, reactions and biological evaluation of some novel thienothiophene derivatives Mohamed, Mounir Abbas Ali Salah, Hanan El-Saghier, Ahmed Mohamed Mohamed Chalcone Isoxazole Diazepine Oxazepine Thienothiophene Antibacterial activity Synthesis of some new bis(chalcones)-based thienothiophene derivatives and study of their synthetic utilities as building blocks for new bis(thiazole), bis(dihydropyran), bis(dihydro pyridine), bis(isoxazoles), bis(pyrazoles), bis(hydropyrimidinethiones), bis(tetrahydro diazepines, oxazepines) and bis(dihydrobenzodiazepnies, benzoxazepines) each linked to a thienothiophene core, is reported. Biological evaluation of the obtained compounds as antibacterial agents was achieved. Compounds 4b, 4c, 7a, 6a, 9a and 11b were found to be very potent against P. aeruginosa, E. coli and K. pneumonia. Atlanta Publishing House LLC 2019-09-30 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://www.eurjchem.com/index.php/eurjchem/article/view/1850 10.5155/eurjchem.10.3.209-217.1850 European Journal of Chemistry; Vol. 10 No. 3 (2019): September 2019; 209-217 2153-2257 2153-2249 eng https://www.eurjchem.com/index.php/eurjchem/article/view/1850/pdf_1850 Copyright (c) 2019 Authors