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Stereochemistry of tropane alkaloid of convolvine and their derivatives Turgunov, Kambarali Kuchkarovich Kadirova, Dilfuza Okmanov, Rasul Aripova, Salima Fazilovna Tashkhodjaev, Bakhodir Convolvine Convolamine Tropane alkaloids N-Benzylconvolvine X‐ray crystallography Convolvulus subhirsutus Structures of alkaloid convolvine (1) isolated from Convolvulus subhirsutus and its derivatives-convolamine(N-methylconvolvine) (2) and hydrochloride of N-benzylconvolvine (3) have been determined by single crystal X-ray diffraction technique. Compounds were crystallized in monoclinic space groups having four molecules in unit cell. All compounds contain a bicyclic ring system of tropane, where piperidine rings in all case adopt chair conformation. Hydrogen atom and methyl- and benzyl-substituents located in nitrogen atom of studied compounds occupy equatorial positions. The substituent of tropane core- the veratroyloxy group containing in all compound molecules is an α-axial oriented relative to the tropane core. In crystal structures of compound 1 and 2, the molecules are located in the distance of van der Waals interactions. The H-bond between the anion Cl and the proton of the N atom is observed in the crystal of N-benzylconvolvine hydrochloride (Cl···N 3.337 Å, Cl···H 2.42 Å and Cl-H-N 175°). Atlanta Publishing House LLC 2019-12-31 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://www.eurjchem.com/index.php/eurjchem/article/view/1909 10.5155/eurjchem.10.4.376-380.1909 European Journal of Chemistry; Vol. 10 No. 4 (2019): December 2019; 376-380 2153-2257 2153-2249 eng https://www.eurjchem.com/index.php/eurjchem/article/view/1909/pdf_1909 Copyright (c) 2019 Authors