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Chitosan as an eco-friendly heterogeneous catalyst for Michael type addition reactions. A simple and efficient route to pyridones and phthalazines Khalil, Khaled Al-Matar, Hamad Elnagdi, Mohamed Chitosan Enaminone Michael addition Pyridone Pthalazine Benzylidene Depending on their nature, nitrile activated methylene compounds add readily to β-enaminones in presence of chitosan to yield dienamides, pyridones or pyridine thiones. The dienamides, formed in this manner, can be readily converted to pyridones by stirring in refluxing acetic acid. Reaction of pyridazinones with a mixture containing benzaldehyde, malononitrile and chitosan affords phthalazines that are also produced by reaction of pyridazinone with benzylidene-malononitrile. Atlanta Publishing House LLC 2010-12-22 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://www.eurjchem.com/index.php/eurjchem/article/view/211 10.5155/eurjchem.1.4.252-258.211 European Journal of Chemistry; Vol. 1 No. 4 (2010): December 2010; 252-258 2153-2257 2153-2249 eng https://www.eurjchem.com/index.php/eurjchem/article/view/211/PDF