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Pharmaceutical organic salt: Disordered crystal structure of levofloxacin with γ-resorcylic acid Mashhadi, Syed Muddassir Ali Tahir, Muhammad Nawaz Apperley, David Bhatti, Moazzam Hussain Ashfaq, Muhammad Yunus, Uzma SC-XRD SS-NM R Organic salt Levofloxacin γ-Resorcylic acid Disordered crystal structure This study reports an organic salt prepared from an antibacterial drug, levofloxacin and antioxidant γ-resorcylic acid. A simple preparation method leads to a crystal with disordered structure. The idea is to prepare an organic salt comprising of pharmaceutically acceptable acidic and basic components. The salt is characterised by IR, solid state NMR, and single crystal XRD. Crystal data for C25H26N3O8F: triclinic, space group P-1 (no. 2), a = 7.0037(8) Å, b = 12.764(3) Å, c = 13.909(3) Å, α = 104.821(4)°, β = 92.039(4)°, γ = 95.334(4)°, V = 1194.6(4) Å3, Z = 2, T = 296(2) K, μ(MoKα) = 0.113 mm-1, Dcalc = 1.433 g/cm3, 16879 reflections measured (5.048° ≤ 2Θ ≤ 54.186°), 5139 unique (Rint = 0.0663, Rsigma = 0.0975) which were used in all calculations. The final R1 was 0.1121 (I>2σ(I)) and wR2 was 0.2505 (all data). SC-XRD analysis shows that the crystal packing is stabilized by strong H-bonding of type N-H···O and comparatively weak interactions of type C-H···O, C-H···π and off-set π···π stacking. Atlanta Publishing House LLC 2021-09-30 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf text/plain https://www.eurjchem.com/index.php/eurjchem/article/view/2134 10.5155/eurjchem.12.3.323-328.2134 European Journal of Chemistry; Vol. 12 No. 3 (2021): September 2021; 323-328 2153-2257 2153-2249 eng https://www.eurjchem.com/index.php/eurjchem/article/view/2134/pdf_2134 https://www.eurjchem.com/index.php/eurjchem/article/view/2134/2691 Copyright (c) 2021 Authors