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oai:ojs.www.eurjchem.com:article/2155 2022-04-02T04:44:19Z eurjchem:ART driver

Highly efficient fluorescence resonance energy transfer in co-encapsulated BODIPY nanoparticles Hewavitharanage, Priyadarshine Steele, Launa Dickenson, Isaac Encapsulation Amphiphilic polymer Polymer nanoparticles Fluorescence enhancement Boron-dipyrromethene (BODIPY) Fluorescence resonance energy transfer Fluorescence resonance energy transfer (FRET) is a powerful tool used in a wide range of applications due to its high sensitivity and many other advantages. Co-encapsulation of a donor and an acceptor in nanoparticles is a useful strategy to bring the donor-acceptor pair in proximity for FRET. A highly efficient FRET system based on BODIPY-BODIPY (BODIPY:  boron-dipyrromethene) donor-acceptor pair in nanoparticles was synthesized. Nanoparticles were formed by co-encapsulating a green emitting BODIPY derivative (FRET donor, lmax = 501 nm) and a red emitting BODIPY derivative (FRET acceptor, lmax = 601 nm) in an amphiphilic polymer using the precipitation method. Fluorescence measurements of encapsulated BODIPY in water following 501 nm excitation caused a 3.6 fold enhancement of the acceptor BODIPY emission at 601 nm indicating efficient energy transfer between the green emitting donor BODIPY and the red emitting BODIPY acceptor with a 100 nm Stokes shift. The calculated FRET efficiency was 96.5%. Encapsulated BODIPY derivatives were highly stable under our experimental conditions. Atlanta Publishing House LLC 2021-12-31 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://www.eurjchem.com/index.php/eurjchem/article/view/2155 10.5155/eurjchem.12.4.361-367.2155 European Journal of Chemistry; Vol. 12 No. 4 (2021): December 2021; 361-367 2153-2257 2153-2249 eng https://www.eurjchem.com/index.php/eurjchem/article/view/2155/pdf_2155 Copyright (c) 2021 Authors