2026-05-16T07:13:10Z https://www.eurjchem.com/index.php/eurjchem/oai

oai:ojs.www.eurjchem.com:article/2687 2025-09-30T05:27:11Z eurjchem:ART driver

Synthesis and characterization of 2-formylthymol-based azo-aldehyde dyes: Probing their efficacy as a radical scavenger in antioxidant applications Girase, Kishor Jaysing Dandge, Santosh Venkatrao Chaudhari, Mangal Arun Bendre, Ratnamala Subhash α-Amylase Antioxidants Diazotization 2-Formylthymol Azo-aldehyde dye Reimer-Tiemann reaction A new series of azo-aldehyde dyes has been derived by performing a diazocoupling reaction between 2-isopropyl-5-methyl phenol and diazonium salts obtained by diazotization of differently substituted aromatic amines. The structures of newly synthesized azo-aldehydes were confirmed by modern analytical spectroscopic techniques such as 1H NMR, 13C NMR, FT-IR, and Mass. Thereafter, all synthesized azo-aldehyde dyes were evaluated for their in vitro antibacterial activity against S. aureus, S. typhumurium, E. coli, and P. aeruginosa strains using the plate method. The formed compounds were also evaluated for antioxidant activity. The present results provide new data to support that the thymol-based azo-aldehyde dyes have a potential to explore a variety of applications in the modern field of molecules and materials of high biological relevance. Atlanta Publishing House LLC 2025-09-30 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://www.eurjchem.com/index.php/eurjchem/article/view/2687 10.5155/eurjchem.16.3.319-326.2687 European Journal of Chemistry; Vol. 16 No. 3 (2025): September 2025; 319-326 2153-2257 2153-2249 eng https://www.eurjchem.com/index.php/eurjchem/article/view/2687/2968 Copyright (c) 2025 Kishor Jaysing Girase, Santosh Venkatrao Dandge, Mangal Arun Chaudhari, Ratnamala Subhash Bendre https://creativecommons.org/licenses/by-nc/4.0