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oai:ojs.www.eurjchem.com:article/336 2011-06-30T10:44:15Z eurjchem:ART driver

A novel and efficient approach for the synthesis of new halo substituted 2-arylpyrazolo[4,3-c] coumarin derivatives Lokhande, Pradeep Hasanzadeh, Kamal Konda, Shankaraiah Guruvaiah Iodine Lactonisation Deallylation 2-Arylpyrazolo[4 3-c]coumarins Oxidation Iodination A convenient protocol for the efficient synthesis of 2-arylpyrazolo[4,3-c]coumarins is described. The synthesis route involves molecular iodine catalyzed oxidative cyclization of 1-phenyl-3-(2'-hydroxyaryl)-4-formyl pyrazoles in dimethylsulfoxide. During the lactonisation of 4-formylpyrazoles, we found that iodine was incorporated into the unsubstituted O/P position of the 3-(2'-hydroxyaryl) group. Under similar conditions o-allyloxy derivative of pyrazoles gave same corresponding lactone derivatives by deallylation, lactonisation, and iodination in one step. Atlanta Publishing House LLC 2011-06-30 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://www.eurjchem.com/index.php/eurjchem/article/view/336 10.5155/eurjchem.2.2.223-228.336 European Journal of Chemistry; Vol. 2 No. 2 (2011): June 2011; 223-228 2153-2257 2153-2249 eng https://www.eurjchem.com/index.php/eurjchem/article/view/336/PDF