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Substituted Quinolinones. Part 16. Preparation and reactions of 3-(4-hydroxy-1-methyl-2-oxo-1,2-dihydroquinolin-3-yl)-3-oxopropanoic acid Abass, Mohamed Mohamed, Elhossain Ali Ismail, Mostafa Mohamed Mayas, Aisha Saleh Quinolin-2(1H)-one b-Keto-carboxylic acid Pyrano[3 2-c]quinoline Knoevenagel condensation Heterocyclization reactions Organic synthesis Preparation of quinolinyl-3-oxopropanoic acid was accomplished by hydrolysis of pyranoquinolinedione, in aqueous alkaline medium. The chemical behavior of this β-keto acid towards nitrosation, coupling with a diazonium salt, esterification, condensation with 2,2-diethoxyethanamine, hydrazinolysis, Knoevenagel condensation with isatine, salicylaldehyde, 3-formylquinolones, and 3-formylchromone, was investigated. Also many of the products of these reactions were obtained using either pyranoquinolinedione 1 or β-keto acid 2, under the same conditions. Atlanta Publishing House LLC 2011-09-30 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://www.eurjchem.com/index.php/eurjchem/article/view/351 10.5155/eurjchem.2.3.378-387.351 European Journal of Chemistry; Vol. 2 No. 3 (2011): September 2011; 378-387 2153-2257 2153-2249 eng https://www.eurjchem.com/index.php/eurjchem/article/view/351/PDF