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oai:ojs.www.eurjchem.com:article/365 2011-06-30T10:44:15Z eurjchem:ART driver

Utility of 2-cyano-3-phenyl-2-propenoyl chloride as Michael’s acceptor in heterocyclic synthesis with mono- and bi-dentate nucleophiles Shiba, Sayed Ahmed Madkour, Hassan Mohamed Fawzy Hamed, Ashraf Ahmed Sayed, Hatem Mohamed El-Hashash, Maher Abd El-aziz Mono- and bi-dentate nucleophiles 2-propenoyl chloride Benzoxazinone Quinazolinone Oxadiazole Benzoxazole (E) 2-Cyano-3-phenyl-2-propenoyl chloride reacts with nitrogen, oxygen and sulphur mono- and bi-dentate nucleophilic reagents to give the amide derivatives, the ester derivatives, as well as some heterocyclic systems, namely quinazolinone, pyridopyrimidine and benzothiazepine. Cyclization of some obtained amides affords the benzoxazinones, quinazolinone, whereas that of other amides yields oxadiazole and benzoxazole, respectively. Atlanta Publishing House LLC 2011-06-30 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://www.eurjchem.com/index.php/eurjchem/article/view/365 10.5155/eurjchem.2.2.200-205.365 European Journal of Chemistry; Vol. 2 No. 2 (2011): June 2011; 200-205 2153-2257 2153-2249 eng https://www.eurjchem.com/index.php/eurjchem/article/view/365/PDF