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oai:ojs.www.eurjchem.com:article/479 2011-12-31T08:09:40Z eurjchem:ART driver

Synthesis and reactions of 3-aminotetrachloroquinazolin-2,4-dione Hassan, Mamdouh Adly Younes, Ahmed Mohamed Mosalem Taha, Mohamed Mobark Abdel-Monsef, Abou-Bakr Haredy Quinazolinedione Hydrazine hydrate Anti-inflammatory Tetrachloroquinazolindione N-Phenylsulphonyloxytetrachlorophthalimide 3-(N-acetylamino)tetrachloroquinazolindione N-phenylsulphonyloxytetrachlorophthalimide was obtained by treatment of N-hydroxy tetrachlorophthalimide with benzenesulphonyl chloride. Also, the titled compound 3 was obtained by reaction of compound 2 with hydrazine hydrate via Lossen rearrangement. Compound 3 used as starting material for the synthesis of new pyrimidine and quinazolinedione derivatives containing four chlorine atoms which have pharmacological activity. Atlanta Publishing House LLC 2011-12-31 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://www.eurjchem.com/index.php/eurjchem/article/view/479 10.5155/eurjchem.2.4.514-518.479 European Journal of Chemistry; Vol. 2 No. 4 (2011): December 2011; 514-518 2153-2257 2153-2249 eng https://www.eurjchem.com/index.php/eurjchem/article/view/479/PDF