2026-05-12T19:21:38Z https://www.eurjchem.com/index.php/eurjchem/oai

oai:ojs.www.eurjchem.com:article/482 2012-12-30T22:55:20Z eurjchem:ART driver

Spectrophotometric investigation of DL-tryptophan in the presence of Ni(II) or Co(II) ions Altun, Ozlen Bilcen, Selin DL-Tryptophan Biological activity Gibbs free energy Spectrophotometry Dissociation constant Potentiometric titration In the present study, synthesis of transition metal complexes of DL-tryptophan with metal precursors such as nickel (II) and cobalt (II) ions in water under refluxing conditions and optimization of the reactions to obtain the composition of complexes in water solutions has been reported. The preparation and structural elucidation of the complexes was undertaken by using physico-chemical, potentiometric titration and spectroscopic methods (UV/Vis, FT-IR and XRD). Comparisons of the spectral measurements of DL-tryptophan with those of the nickel (II) and cobalt (II) complexes are useful in determining the atoms of the ligand that are coordinated to the metal ion. In addition, K (dissociation constant) and ΔG (Gibbs free energy) values were calculated using the Babko and Stanley & Turners methods. Antibacterial and antifungal activities of the complexes were studied screened against bacteria and fungi. The activity data shows that and cobalt complexes of DL-tryptophan are more potent than the DL-tryptophan. Atlanta Publishing House LLC 2012-12-31 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://www.eurjchem.com/index.php/eurjchem/article/view/482 10.5155/eurjchem.3.4.411-415.482 European Journal of Chemistry; Vol. 3 No. 4 (2012): December 2012; 411-415 2153-2257 2153-2249 eng https://www.eurjchem.com/index.php/eurjchem/article/view/482/PDF