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oai:ojs.www.eurjchem.com:article/630 2012-12-31T23:10:35Z eurjchem:ART driver

Application of sulfonic acid functionalized nanoporous silica (SBA-Pr-SO3H) in the solvent free synthesis of (E)-arylidene-1,3-dihydroindole-2-ones Gholamzadeh, Parisa Ziarani, Ghodsi Mohammadi Badiei, Alireza Bahrami, Zohreh Oxindole SBA-Pr-SO3H Green synthesis Solvent free reaction Tyrosin kinase inhibitor Arylidene-1 3-dihydroindole-2-ones An efficient and green condensation reaction is developed for the synthesis of (E)-arylidene-1,3-dihydroindole-2-ones; (1), using heterogeneous nanoporous acid catalyst of SBA-Pr-SO3H with pore size, 6 nm in solvent free condition. Arylidene-1,3-dihydroindole-2-ones have many pharmaceutical properties such as Tyrosin kinase inhibiton. This method has the advantages of short reaction time, isolation ease of the products, excellent yields and recyclable catalyst. Atlanta Publishing House LLC 2012-09-30 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://www.eurjchem.com/index.php/eurjchem/article/view/630 10.5155/eurjchem.3.3.279-282.630 European Journal of Chemistry; Vol. 3 No. 3 (2012): September 2012; 279-282 2153-2257 2153-2249 eng https://www.eurjchem.com/index.php/eurjchem/article/view/630/PDF