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oai:ojs.www.eurjchem.com:article/71 2011-04-06T05:18:46Z eurjchem:ART driver

Novel isoquinoline derivatives from isochromen-1,3-dione Mahmoud, Mahmoud Refaee El-Shahawi, Manal Mohamed El-Bordany, Eman Abd El-Fattah Abu El-Azm, Fatma Saber Mohamed Isochromene-1 3-dione Isoquinolines 2-Cyanoethanoic hydrazide Nitrogen nucleophiles A number of novel isoquinoline derivatives have been synthesized using the readily obtainable (E)-4-(3,4-dimethoxybenzylidene)-4H-isochromene-1,3-dione, 2, via the reaction with different nitrogen nucleophiles such as cyanoethanoic hydrazide, cyclohexylamine, 2-aminothiophenol and p-toluenesulfonohydrazide. Furthermore, the reactivity of 2 towards thiophenol, and ethylcyanoacetate has been investigated. Atlanta Publishing House LLC 2010-06-15 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://www.eurjchem.com/index.php/eurjchem/article/view/71 10.5155/eurjchem.1.2.134-139.71 European Journal of Chemistry; Vol. 1 No. 2 (2010): June 2010; 134-139 2153-2257 2153-2249 eng https://www.eurjchem.com/index.php/eurjchem/article/view/71/PDF