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oai:ojs.www.eurjchem.com:article/860 2014-03-31T01:48:51Z eurjchem:ART driver

Synthesis, reactions, antioxidant and anticancer evaluation of some novel coumarin derivatives using ethyl 2-(2-oxo-4-phenyl-2H-chromen-7-yloxy) acetate as a starting material Halawa, Ahmed Hamdy Hassan, Ahmed Abd El-Hameed El-Nassag, Mohamed Ahmed Abd El-All, Mahmoud Mohamed Abd El-Jaleel, GehadAbd El-Raheem Eliwa, Essam Mohamed Bedair, Ahmed Hammam Triazole Oxadiazole Cytotoxicity Benzoimidazole Antioxidant activity Coumarinacetohydrazide We report on the synthesis of new coumarin derivatives coupled with heterocyclic and bifunctionalized moieties at position 7. The proposed structures were confirmed by correct elemental analysis and spectral data (IR, MS, 1H NMR and 13C NMR). Some selected derivatives were also screened for their antioxidant and anticancer activities. The results indicated that 7-{[6-(4-nitrophenyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazin-3-yl]methoxy}-4-phenyl-H-chromen-2-one has the highest antioxidant and anticancer activity in tested compounds. Atlanta Publishing House LLC 2014-03-31 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://www.eurjchem.com/index.php/eurjchem/article/view/860 10.5155/eurjchem.5.1.111-121.860 European Journal of Chemistry; Vol. 5 No. 1 (2014): March 2014; 111-121 2153-2257 2153-2249 eng https://www.eurjchem.com/index.php/eurjchem/article/view/860/PDF_860