2026-03-13T08:12:57Z https://www.eurjchem.com/index.php/eurjchem/oai

oai:ojs.www.eurjchem.com:article/1242 2015-09-30T05:16:04Z eurjchem:ART driver

Synthesis of some novel benzimidazole derivatives and their biological evaluation Gund, Dnyandev Radhu Rao, Balivada Venkata Satyasai Varaprasad Mandhare, Pandurang Narayanrao Vaidya, Sanjay Dashrath Alkylation Benzimidazole Suzuki coupling Antifungal activity Phenyl boronic acid Antibacterial activity A series of novel benzimidazole derivatives have been synthesized by the condensation of o-phenylenediamine with 4-bromophenoxy acetic acid and product obtained was alkylated at the benzimidazole -NH with different electrophilic reagents. Subsequent reactions of the products by the Suzuki Coupling between benzimidazole derivatives and phenylboronic acid derivatives were accomplished. All these compounds were characterized by FT-IR, 1H NMR, MS and elemental analysis. These compounds were screened for their potential antibacterial and antifungal activities. This exhibited some promising results towards testing organism in-vitro. Atlanta Publishing House LLC 2015-09-30 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion application/pdf https://www.eurjchem.com/index.php/eurjchem/article/view/1242 10.5155/eurjchem.6.3.270-274.1242 European Journal of Chemistry; Vol. 6 No. 3 (2015): September 2015; 270-274 2153-2257 2153-2249 eng https://www.eurjchem.com/index.php/eurjchem/article/view/1242/pdf_1242