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2014-03-31T01:48:51Z
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One-pot, multicomponent synthesis of symmetrical Hantzsch 1,4-dihydropyridine derivatives using glycerol as clean and green solvent
Sohal, Harvinder Singh
Goyal, Arun
Sharma, Rajeev
Khare, Rajshree
One-pot
Glycerol
Aldehydes
Catalyst free
1
4-Dihydropyridine
Hantzsch condensation
Multi component, one pot synthesis of symmetrical 1,4-dihydropyridine derivatives from the condensation of ethyl/methyl acetoacetate, aromatic/aliphatic aldehyde and ammonium acetate has been described using glycerol, as economical, easily available and environmentally benign reagent. The targeted molecules were obtained in high purity and excellent yield without use of any additional catalyst and methodology from readily available starting materials.
Atlanta Publishing House LLC
2014-03-31
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
application/pdf
https://www.eurjchem.com/index.php/eurjchem/article/view/943
10.5155/eurjchem.5.1.171-175.943
European Journal of Chemistry; Vol. 5 No. 1 (2014): March 2014; 171-175
2153-2257
2153-2249
eng
https://www.eurjchem.com/index.php/eurjchem/article/view/943/PDF_943