European Journal of Chemistry

Physicochemical studies and biological activity of mixed ligand complexes involving bivalent transition metals with a novel Schiff base and glycine as a representative amino acid

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Published: Jun 30, 2014
DOI: https://doi.org/10.5155/eurjchem.5.2.328-333.1025
Keywords:
Glycine, Schiff base, Amino acid, Electronic spectra, Antibacterial activity, Mixed-ligand complexes
Section
Research Article
Issue
Vol. 5 No. 2 (2014): June 2014
Dates
Received 2014-01-29
Accepted 2014-02-18
Published 2014-06-30


Main Article Content

Abeer Taha Abedel Karim
Department of Chemistry, Faculty of Science, Cairo University, Cairo, 12613 Egypt
Ahmed Abdou El-Sherif
Department of Chemistry, Faculty of Arts and Science, Northern Borders University, Rafha, 156, Kingdom of Saudi Arabia

Abstract

The mixed-ligand complexes of Co(II), Ni(II), Mn(II) and Zn(II) with 2-aminomethyl thiophenyl-4-bromosalicylaldehyde Schiff base (ATS) and glycine as a representative example of amino acids have been achieved. These complexes namely [Ni(ATS)(Gly)] (1), [Co(ATS)(Gly)].H2O (2) [Mn(ATS)(Gly)].2H2O (3), and [Zn(ATS)(Gly)] (4) were characterized by elemental, molar conductance, infrared, magnetic moment, and electronic spectra. ATS behaves as mononegatively charged bidentate ligand with coordination through azomethine nitrogen and phenolate oxygen groups while glycine acts as monobasic bidentate ligand is coordinated via amino and ionized carboxylate group after deprotonation. The low molar conductance values suggest the non-electrolytic nature of these complexes. The magnetic and spectral data indicates a square planar geometry for Ni(II) complex, tetrahedral geometry for Zn(II) and octahedral geometry for both Mn(II) and Co(II) complexes. The isolated chelates have been screened for their antimicrobial activity.


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Karim, A. T. A.; El-Sherif, A. A. Physicochemical Studies and Biological Activity of Mixed Ligand Complexes Involving Bivalent Transition Metals With a Novel Schiff Base and Glycine As a Representative Amino Acid. Eur. J. Chem. 2014, 5, 328-333.

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