European Journal of Chemistry

FeCl3-catalysed C-N coupling reaction between cyclic ethers and heterocyclic amines



Main Article Content

Suresh Mani
Mashood Ahamed Fazul Mohamed
Abdul Khader Karakkakal
Syed Ali Padusha Mohamed Khan

Abstract

A series of 2-hydroxypyrrolidine/piperidine derivatives (4a-h)/(4i-m) were prepared by reacting 2,3-dihydrofuran (2a)/3,4-dihydro-2H-pyran (2b) with various heterocyclic amines (3a-h), using FeCl3.6H2O as catalyst. The synthesized compounds were characterized by various physic chemical techniques such as elemental analysis and spectral analysis viz, 1H NMR, 13C NMR and Mass.


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Mani, S.; Mohamed, M. A. F.; Karakkakal, A. K.; Khan, S. A. P. M. FeCl3-Catalysed C-N Coupling Reaction Between Cyclic Ethers and Heterocyclic Amines. Eur. J. Chem. 2014, 5, 612-617.

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Supporting Agencies

University Grants Commission, New Delhi, Major Research Project (Ref. No, 41-261/2012 (SR), Dated, 13-07-2012), Sophisticated Test and Instrumentation Centre (STIC), Cochin and Sophisticated Analytical Inst. Fac., Indian Institute of Technology, India
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