European Journal of Chemistry

Synthesis, reactions and antimicrobial activity of benzothiazoles

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Published: Jun 30, 2015
DOI: https://doi.org/10.5155/eurjchem.6.2.98-106.1161
Keywords:
Pyrrole, Schiff's base, Benzothiazole, Thioglycolic acid, Mercaptotriazole, Antimicrobial activity
Section
Research Article
Issue
Vol. 6 No. 2 (2015): June 2015
Dates
Received 2014-09-23
Accepted 2015-01-11
Published 2015-06-30


Main Article Content

Eman Mostafa Abbas
Department of Chemistry, Natural and Microbial Products, National Research Center, Dokki, Giza, 12622, Egypt
Marwa Saied Salem
Synthetic Organic Chemistry Laboratory, Chemistry Department, Faculty of Science, Ain Shams University, Abbasiya, Cairo, 11566, Egypt
Asmaa Fathy Kassem
Department of Chemistry, Natural and Microbial Products, National Research Center, Dokki, Giza, 12622, Egypt
Sherein Ismail Abd El-Moez
Microbiology and Immunology Department, Veterinary Division, National Research Center, Dokki, Giza, 12622, Egypt
Mohamed Youssef El-Kady
Synthetic Organic Chemistry Laboratory, Chemistry Department, Faculty of Science, Ain Shams University, Abbasiya, Cairo, 11566, Egypt

Abstract

Benzothiazoles have been proven to be potent antimicrobial agents. In this study, 3-(5,6-dimethoxy-2-oxo-1,3-benzothiazol-3(2H)-yl)propanohydrazide has been utilized as a scaffold for synthesis of pyrrole, indolylidene, pyrazoles, mercaptotriazole, oxadiazole, triazole and oxothiazolidine derivatives. Structures of the synthesized compounds were elucidated on the basis of elemental analyses and spectral data. All the synthesized compounds were screened for their antimicrobial activity.


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How to Cite
(1)
Abbas, E. M.; Salem, M. S.; Kassem, A. F.; Abd El-Moez, S. I.; El-Kady, M. Y. Synthesis, Reactions and Antimicrobial Activity of Benzothiazoles. Eur. J. Chem. 2015, 6, 98-106.

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Microbiology and Immunology Department, Veterinary Division, National Research Center and Microanalytical Center of Cairo University, Cairo, Egypt
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