European Journal of Chemistry

Synthesis, reactions and antimicrobial activity of benzothiazoles



Main Article Content

Eman Mostafa Abbas
Marwa Saied Salem
Asmaa Fathy Kassem
Sherein Ismail Abd El-Moez
Mohamed Youssef El-Kady

Abstract

Benzothiazoles have been proven to be potent antimicrobial agents. In this study, 3-(5,6-dimethoxy-2-oxo-1,3-benzothiazol-3(2H)-yl)propanohydrazide has been utilized as a scaffold for synthesis of pyrrole, indolylidene, pyrazoles, mercaptotriazole, oxadiazole, triazole and oxothiazolidine derivatives. Structures of the synthesized compounds were elucidated on the basis of elemental analyses and spectral data. All the synthesized compounds were screened for their antimicrobial activity.


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Abbas, E. M.; Salem, M. S.; Kassem, A. F.; Abd El-Moez, S. I.; El-Kady, M. Y. Synthesis, Reactions and Antimicrobial Activity of Benzothiazoles. Eur. J. Chem. 2015, 6, 98-106.

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Supporting Agencies

Microbiology and Immunology Department, Veterinary Division, National Research Center and Microanalytical Center of Cairo University, Cairo, Egypt
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