European Journal of Chemistry 2016, 7(1), 135-136. doi:10.5155/eurjchem.7.1.135-136.1360

Application of a multi-component cyclocondensation to develop a bioactive molecular scaffold


Sankar Chatterjee (1,*)

(1) Cephalon, Inc., 145 Brandywine Parkway, West Chester, PA 19380-4245, USA
(*) Corresponding Author

Received: 09 Nov 2015, Accepted: 13 Dec 2015, Published: 31 Mar 2016

Abstract


A molecular scaffold containing a furanoquinoline motif that offered a unique molecular architecture for 5-hydroxytryptamine 6 receptor antagonism was generated by a multi-component cyclization reaction.


Keywords


CNS; 5-HT6; Antagonist; Benzazepine; Furanoquinoline; Cyclocondensation

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DOI: 10.5155/eurjchem.7.1.135-136.1360

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How to cite


Chatterjee, S. Eur. J. Chem. 2016, 7(1), 135-136. doi:10.5155/eurjchem.7.1.135-136.1360
Chatterjee, S. Application of a multi-component cyclocondensation to develop a bioactive molecular scaffold. Eur. J. Chem. 2016, 7(1), 135-136. doi:10.5155/eurjchem.7.1.135-136.1360
Chatterjee, S. (2016). Application of a multi-component cyclocondensation to develop a bioactive molecular scaffold. European Journal of Chemistry, 7(1), 135-136. doi:10.5155/eurjchem.7.1.135-136.1360
Chatterjee, Sankar. "Application of a multi-component cyclocondensation to develop a bioactive molecular scaffold." European Journal of Chemistry [Online], 7.1 (2016): 135-136. Web. 18 Nov. 2019
Chatterjee, Sankar. "Application of a multi-component cyclocondensation to develop a bioactive molecular scaffold" European Journal of Chemistry [Online], Volume 7 Number 1 (31 March 2016)

DOI Link: https://doi.org/10.5155/eurjchem.7.1.135-136.1360

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