European Journal of Chemistry

Synthesis and antimicrobial activity of 1,3-bis-butyl-5-(4-iodophenyl)-1,3,5-triazacyclohexane



Main Article Content

Leila Lefrada
Randolf Köhn
Souhila Malki
Wissam Mazouz
Ahcene Bouchemma
Meriem Hadjem

Abstract

This work describes the synthesis, structural characterization and antibacterial activities of 1,3,5-triazacyclohexane type of new compound 1,3-bis-butyl-5-(4-iodophenyl)-1,3,5-triazacyclohexane. The new triazacyclohexanes (R3TAC) with mixed aryl and alkyl N-substituents are synthesized by the reaction of a 1:2 mixture of 4-iodoaniline and n-butylamine with formalin. The synthesized compounds were characterized by spectral analysis IR, 1H NMR and 13C NMR. The compound was screened for it’s antibacterial activity against Gram-positive and Gram-negative bacteria by the diffusion method on agar medium.


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Lefrada, L.; Köhn, R.; Malki, S.; Mazouz, W.; Bouchemma, A.; Hadjem, M. Synthesis and Antimicrobial Activity of 1,3-Bis-Butyl-5-(4-Iodophenyl)-1,3,5-Triazacyclohexane. Eur. J. Chem. 2017, 8, 82-84.

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Author Biography

Leila Lefrada, Laboratory of Applied Chemistry and Materials Technology University Larbi Ben M’hidi of Oum El Bouaghi, 04000, Algeria


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Supporting Agencies

Laboratory of Applied Chemistry and Materials Technology of the University Larbi Ben M’hidi of Oum El Bouaghi, Research Fund (Project No, E03020130036), Algeria.
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