Email this article 
Hide
Show all
OPEN ACCESS | 
PEER-REVIEWED |
RESEARCH ARTICLE
|
DOWNLOAD PDF
|
VIEW FULL-TEXT PDF
| TOTAL VIEWS
Ecofriendly and simple synthesis of pyrano[3,2-c]quinolone in water via an efficient one-pot three-component reaction
Ibrahim Ali Radini (1)
, Sameh Ramadan El-Gogary (2) , Mohamed Sabri Mostafa (3,*) , Bander Alnagei (4) , Mohammed Mudarbish (5) , Shadad Dash (6) (1) Chemistry Department, Faculty of Science, Jazan University, Jazan, 2079, Kingdom of Saudi Arabia
(2) Chemistry Department, Faculty of Science, Damietta University, New Damietta, 34518, Egypt
(3) Chemistry Department, Faculty of Science, Jazan University, Jazan, 2079, Kingdom of Saudi Arabia
(4) Chemistry Department, Faculty of Science, Jazan University, Jazan, 2079, Kingdom of Saudi Arabia
(5) Chemistry Department, Faculty of Science, Jazan University, Jazan, 2079, Kingdom of Saudi Arabia
(6) Chemistry Department, Faculty of Science, Jazan University, Jazan, 2079, Kingdom of Saudi Arabia
(*) Corresponding Author
Received: 28 Dec 2017 | Revised: 27 Jan 2018 | Accepted: 28 Jan 2018 | Published: 31 Mar 2018 | Issue Date: March 2018
Abstract
Pyrano[3,2-c]quinolones are commonly found in alkaloids, manifesting diverse biological activities. In this work, 2-amino-6-methyl-5-oxo-4-substituted-5,6-dihydro-4H-pyrano[3,2-c]quinoline-3-carbonitriles and ethyl 2-amino-4-(substituted)-6-methyl-5-oxo-5,6-dihydro-4H-pyrano[3,2-c]quinoline-3-carboxylates have been synthesized efficiently from reaction of 4-hydroxy-1-methylquinolin-2(1H)-one, aldehydes and active methylene nitriles in one-pot three component reaction in aqueous medium, containing catalytic amount of ethanolamine resulting in 70-95% yields.
Announcements
Our editors have decided to support scientists to publish their manuscripts in European Journal of Chemistry without any financial constraints.
1- The article processing fee will not be charged from the articles containing the single-crystal structure characterization or a DFT study between September 15, 2023 and October 31, 2023 (Voucher code: FALL2023).
2. A 50% discount will be applied to the article processing fee for submissions made between September 15, 2023 and October 31, 2023 by authors who have at least one publication in the European Journal of Chemistry (Voucher code: AUTHOR-3-2023).
3. Young writers will not be charged for the article processing fee between September 15, 2023 and October 31, 2023 (Voucher code: YOUNG2023).
Editor-in-Chief
European Journal of Chemistry
Keywords
Full Text:
PDF
DOI: 10.5155/eurjchem.9.1.44-48.1679
Links for Article
| | | | | | |
| | | | | | |
| | | |
Related Articles
Article Metrics
This Abstract was viewed 1541 times |
PDF Article downloaded 623 times
Funding information
Jazan University (Project no. 019-FS3), Jazan, 2079, Kingdom of Saudi Arabia.
Citations
[1]. Kamlesh Saini, Ashok K. Raigar, Manju, Dinesh K. Jangid, Jaya Mathur, Surbhi Dhadda, Anjali Guleria
Tandem Protocol for the Synthesis of Pyrano[3,2-c]quinolone Derivatives Using Taurine as a Green Bio-Organic Catalyst in Aqueous Medium
The Journal of Organic Chemistry 87(21), 13734, 2022
DOI: 10.1021/acs.joc.2c01403
References
[1]. Asghari, S.; Ramezani, S.; Mohseni, M. Chin. Chem. Lett. 2014, 25, 431-434.
https://doi.org/10.1016/j.cclet.2013.12.010
[2]. Hassanin, H.; Ibrahim, M.; Alnamer, Y. Turk. J. Chem. 2012, 36, 682-699.
[3]. Fujita, Y.; Oguri, H.; Oikawa, H. J. Antibiot. 2005, 58, 425-427.
https://doi.org/10.1038/ja.2005.56
[4]. Chen, J. J.; Chen, P. H.; Liao, C. H.; Huang, S. Y.; Chen, I. S. J. Nat. Prod. 2007, 70, 1444-1448.
https://doi.org/10.1021/np070186g
[5]. Isaka, M.; Tanticharoen, M.; Kongsaeree, P.; Thebtaranonth, Y. J. Org. Chem. 2001, 66, 4803-4808.
https://doi.org/10.1021/jo0100906
[6]. Magedov, V.; Madhuri, M.; Marcia, O.; Adriana, D.; Snezna, R.; Severine, V.; Wim, S.; Nikolai, E.; Pavel, U.; Eerik, E.; Erica, K.; Paul, T.; Mikhail, A.; Alexander, K. J. Med. Chem. 2008, 51(8), 2561-2570.
https://doi.org/10.1021/jm701499n
[7]. Kamperdick, C.; Van, N. H.; Van Sung, T.; Adam, G. Phytochemistry 1999, 50, 177-181.
https://doi.org/10.1016/S0031-9422(98)00500-7
[8]. Chen, I. S.; Wu, S. J.; Tsai, I. L.; Wu, T. S.; Pezzuto, J. M.; Lu, C.; Chai, H.; Suh, N.; Teng, M. J. Nat. Prod. 1994, 57, 1206-1211.
https://doi.org/10.1021/np50111a003
[9]. Heiner, E. Molecules 2012, 17, 1074-1102.
https://doi.org/10.3390/molecules17011074
[10]. Bhupathi, R.; Madhu, B.; Devi, R.; Reddy, R.; Dubey, K. J. Heterocycl. Chem. 2016, 53(6), 1911-1916.
https://doi.org/10.1002/jhet.2506
[11]. Shehata, A. S.; Faida, H.; Moustafa, M. A.; Mashaly, M. M. J. Am. Sci. 2011, 7(11), 240-242.
[12]. Kumar, N. V.; Rajendran, S. P. Heterocycl. Commun. 2004, 10, 289-294.
[13]. Dodia, N.; Shah, A. Heterocycl. Commun. 2001, 7, 289-294.
https://doi.org/10.1515/HC.2001.7.3.289
How to cite
The other citation formats (EndNote | Reference Manager | ProCite | BibTeX | RefWorks) for this article can be found online at: How to cite item
DOI Link: https://doi.org/10.5155/eurjchem.9.1.44-48.1679
| 
| 
| 
| 
| 
| 
| 
| 
| 
| 
| 
| 
| 
| 
| 
Save to Zotero
Save to Mendeley
European Journal of Chemistry 2018, 9(1), 44-48 | doi: https://doi.org/10.5155/eurjchem.9.1.44-48.1679 | Get rights and content
Refbacks
- There are currently no refbacks.
Copyright (c) 2018 Authors
This work is published and licensed by Atlanta Publishing House LLC, Atlanta, GA, USA. The full terms of this license are available at http://www.eurjchem.com/index.php/eurjchem/pages/view/terms and incorporate the Creative Commons Attribution-Non Commercial (CC BY NC) (International, v4.0) License (http://creativecommons.org/licenses/by-nc/4.0). By accessing the work, you hereby accept the Terms. This is an open access article distributed under the terms and conditions of the CC BY NC License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited without any further permission from Atlanta Publishing House LLC (European Journal of Chemistry). No use, distribution or reproduction is permitted which does not comply with these terms. Permissions for commercial use of this work beyond the scope of the License (http://www.eurjchem.com/index.php/eurjchem/pages/view/terms) are administered by Atlanta Publishing House LLC (European Journal of Chemistry).
© Copyright 2010 - 2023 • Atlanta Publishing House LLC • All Right Reserved.
The opinions expressed in all articles published in European Journal of Chemistry are those of the specific author(s), and do not necessarily reflect the views of Atlanta Publishing House LLC, or European Journal of Chemistry, or any of its employees.
Copyright 2010-2023 Atlanta Publishing House LLC. All rights reserved. This site is owned and operated by Atlanta Publishing House LLC whose registered office is 2850 Smith Ridge Trce Peachtree Cor GA 30071-2636, USA. Registered in USA.