

Identification and characterization of geometrical isomeric photo degradation product of eprosartan using LC-MS and LC-NMR
Ravi Piyushkumar Shah (1)



(1) Department of Pharmaceutical Analysis, National Institute of Pharmaceutical Education and Research (NIPER), SAS Nagar 160062, Punjab, India
(2) Department of Pharmaceutical Analysis, National Institute of Pharmaceutical Education and Research (NIPER), SAS Nagar 160062, Punjab, India
(3) Department of Pharmaceutical Analysis, National Institute of Pharmaceutical Education and Research (NIPER), SAS Nagar 160062, Punjab, India
(*) Corresponding Author
Received: 17 Jun 2010 | Revised: 08 Apr 2011 | Accepted: 02 Nov 2010 | Published: 30 Jun 2011 | Issue Date: June 2011
Abstract

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DOI: 10.5155/eurjchem.2.2.152-157.170
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[1]. Alexander Ccanccapa-Cartagena, Yolanda Pico, Xavier Ortiz, Eric J. Reiner
Suspect, non-target and target screening of emerging pollutants using data independent acquisition: Assessment of a Mediterranean River basin
Science of The Total Environment 687, 355, 2019
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[2]. S. Herrera‐Lopez, M. D. Hernando, E. García‐Calvo, A. R. Fernández‐Alba, M. M. Ulaszewska
Simultaneous screening of targeted and non‐targeted contaminants using an LC‐QTOF‐MS system and automated MS/MS library searching
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DOI: 10.1002/jms.3428

[3]. Rubén M. Maggio, Natalia L. Calvo, Silvana E. Vignaduzzo, Teodoro S. Kaufman
Pharmaceutical impurities and degradation products: Uses and applications of NMR techniques
Journal of Pharmaceutical and Biomedical Analysis 101, 102, 2014
DOI: 10.1016/j.jpba.2014.04.016

[4]. René Holm, David P. Elder
Analytical advances in pharmaceutical impurity profiling
European Journal of Pharmaceutical Sciences 87, 118, 2016
DOI: 10.1016/j.ejps.2015.12.007

[5]. Ravi P. Shah, Archana Sahu, Saranjit Singh
LC-MS/TOF, LC-MSn, on-line H/D exchange and LC-NMR studies on rosuvastatin degradation and in silico determination of toxicity of its degradation products: a comprehensive approach during drug development
Analytical and Bioanalytical Chemistry 405(10), 3215, 2013
DOI: 10.1007/s00216-013-6760-1

[6]. Pradipbhai D. Kalariya, Murali V. N. Kumar Talluri, Vinay D. Gaitonde, Prashant S. Devrukhakar, Ragampeta Srinivas
Quality by design: A systematic and rapid liquid chromatography and mass spectrometry method for eprosartan mesylate and its related impurities using a superficially porous particle column
Journal of Separation Science 37(16), 2160, 2014
DOI: 10.1002/jssc.201301364

[7]. Paul Turnpenny, Anthony Dickie, Jed Malec, Jordan McClements
Retention-directed and selectivity controlled chromatographic resolution: Rapid post-hoc analysis of DMPK samples to achieve high-throughput LC-MS separation
Journal of Chromatography B 1164, 122514, 2021
DOI: 10.1016/j.jchromb.2020.122514

[8]. Saranjit Singh, Tarun Handa, Mallikarjun Narayanam, Archana Sahu, Mahendra Junwal, Ravi P. Shah
A critical review on the use of modern sophisticated hyphenated tools in the characterization of impurities and degradation products
Journal of Pharmaceutical and Biomedical Analysis 69, 148, 2012
DOI: 10.1016/j.jpba.2012.03.044

References
[2]. WHO, Draft Stability Testing of Active Pharmaceutical Ingredients and Pharmaceutical Products, World Health Organization, Geneva, 2007.
[3]. Murakami, T.; Kawasaki, T.; Takemura, A.; Fukutsu, N.; Kishi, N.; Kusu, F. J. Chromatogr. A 2008, 1208, 164-174.
doi:10.1016/j.chroma.2008.08.076
PMid:18778828
[4]. Shah, R. P.; Kumar, V.; Singh, S. Rapid Commun. Mass Spectrom. 2008, 22, 613-622.
doi:10.1002/rcm.3403
PMid:18247406
[5]. Novak, P.; Tepes, P.; Ilijas, M.; Fistric, I.; Bratos, I.; Avdagic, A.; Hamersak, Z.; Markovic, V. G.; Dumic, M. J. Pharm. Biomed. Anal. 2009, 50, 68-72.
doi:10.1016/j.jpba.2009.03.017
PMid:19410412
[6]. Dev, R. V.; Kiran, G. S. U.; Subbaiah, B. V.; Babu, B. S.; Babu, J. M.; Dubey, P. K.; Vyas, K. Magn. Reson. Chem. 2009, 47, 443-448.
doi:10.1002/mrc.2404
PMid:19173350
[7]. Shah, R. P.; Sahu, A.; Singh, S. J. Pharm. Biomed. Anal. 2010, 51, 1037-1046.
doi:10.1016/j.jpba.2009.11.008
PMid:20018473
[8]. Shah, R. P.; Singh, S. J. Pharm. Biomed. Anal. 2010, 53, 755-761.
doi:10.1016/j.jpba.2010.05.005
PMid:20554147
[9]. Hoffman, B. B. in: Brunton, L.L. Goodman & Gilman’s The Pharmacological Basis of Therapeutics, 11th Edition, McGraw-Hill, 859-860, 2006.
[10]. Available at: http://www.accessdata.fda.gov/scripts/cder/drugsatfda/index.cfm?Fuseaction=Search.DrugDetails (accessed on 11 April 2011).
[11]. Hsu, L. C. J. Liq. Chrom. & Rel. Technol. 1998, 21, 1685-1700.
doi:10.1080/10826079808001252
PMCid:1176066
[12]. Xue-Ning, L.; Hong-Rong, X.; Wei-Li, C.; Gang-Yi, L.; Nan-Nan. C.; Chen Y. J. Chromatogr. B 2007, 853, 47-53.
[13]. Ferreirós, N.; Iriarte, G.; Alonsoa, R. M.; Jiménez, R. M.; Ortíz, E. J. Chromatogr. A 2006, 1119, 309-314.
doi:10.1016/j.chroma.2006.02.055
PMid:16542666
[14]. ICH Topic Q1B, Stability Testing: Photostability Testing of New Drug Substances and Products, in: International Conference on Harmonisation, IFPMA, Geneva, 1996.
[15]. Bakshi, M.; Singh, S. J. Pharm. Biomed. Anal. 2002, 28, 1011-1040.
doi:10.1016/S0731-7085(02)00047-X
[16]. Mayer-Helm, B.; Hofbauer, L.; Pani, J. J. Mass. Spectrom. 2010, (Article in Press; doi:10.1002/jms.1757).
[17]. Ge, G. B.; Zhang, R.; Ail, C. Z.; He Y. Q.; Zhang Y. Y.; Liu X. B.; Yang L.; Wang Z. T.; Yang L. Rapid Commun. Mass Spectrom. 2009, 23, 425-432.
doi:10.1002/rcm.3892
PMid:19125430
[18]. Brum, J.; Hannah, R. Rapid Commun. Mass Spectrom. 1997, 11, 1430-1434.
doi:10.1002/(SICI)1097-0231(19970830)11:13<1430::AID-RCM7>3.0.CO;2-5
[19]. Thoma, K.; Kuebler, N.; Reimann, E. Pharmazie 1997, 52, 362-373.
PMid:9229718
[20]. Albini, A.; Fasani, E. in: Tønnesen H. H. The Photostability of Drugs and Drug Formulations, 2nd Edition, Taylor and Francis, 69-71, 2004.
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