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Polyethylene glycol (PEG-400) mediated synthesis of quinoxalines
Lingaiah Nagarapu (1,*)
, Raghu Mallepalli (2) , Glory Arava (3) , Lingappa Yeramanchi (4) (1) Organic Chemistry Division-II, Indian Institute of Chemical Technology, Uppal Road, Hyderabad-500007, India
(2) Department of Chemistry, Sri Venkateswara University, Tirupati-517502, India
(3) Department of Chemistry, Sri Venkateswara University, Tirupati-517502, India
(4) Department of Chemistry, Sri Venkateswara University, Tirupati-517502, India
(*) Corresponding Author
Received: 17 Jun 2010 | Revised: 02 Aug 2010 | Accepted: 10 Aug 2010 | Published: 29 Sep 2010 | Issue Date: September 2010
Abstract
A simple and highly efficient protocol for the synthesis of quinoxaline derivatives from various ortho-phenylenediamines with α-halo ketones under catalyst free conditions is reported by using polyethylene glycol (PEG-400) as an efficient recyclable medium without using any organic co-solvent or additive. This protocol gives wide range of quinoxaline derivatives with high yields.
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DOI: 10.5155/eurjchem.1.3.228-231.172
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Citations
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[2]. Dineshwori Chanu Loukrakpam, Prodeep Phukan
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[3]. Gangadhar B. Gundlewad, Bhagwan. R. Patil
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DOI Link: https://doi.org/10.5155/eurjchem.1.3.228-231.172
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