European Journal of Chemistry

Polyethylene glycol (PEG-400) mediated synthesis of quinoxalines

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Lingaiah Nagarapu
Raghu Mallepalli
Glory Arava
Lingappa Yeramanchi


A simple and highly efficient protocol for the synthesis of quinoxaline derivatives from various ortho-phenylenediamines with α-halo ketones under catalyst free conditions is reported by using polyethylene glycol (PEG-400) as an efficient recyclable medium without using any organic co-solvent or additive. This protocol gives wide range of quinoxaline derivatives with high yields.


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How to Cite
Nagarapu, L.; Mallepalli, R.; Arava, G.; Yeramanchi, L. Polyethylene Glycol (PEG-400) Mediated Synthesis of Quinoxalines. Eur. J. Chem. 2010, 1, 228-231.

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