European Journal of Chemistry 2010, 1(3), 228-231 | doi: https://doi.org/10.5155/eurjchem.1.3.228-231.172 | Get rights and content

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Polyethylene glycol (PEG-400) mediated synthesis of quinoxalines


Lingaiah Nagarapu (1,*) , Raghu Mallepalli (2) , Glory Arava (3) , Lingappa Yeramanchi (4)

(1) Organic Chemistry Division-II, Indian Institute of Chemical Technology, Uppal Road, Hyderabad-500007, India
(2) Department of Chemistry, Sri Venkateswara University, Tirupati-517502, India
(3) Department of Chemistry, Sri Venkateswara University, Tirupati-517502, India
(4) Department of Chemistry, Sri Venkateswara University, Tirupati-517502, India
(*) Corresponding Author

Received: 17 Jun 2010 | Revised: 02 Aug 2010 | Accepted: 10 Aug 2010 | Published: 29 Sep 2010 | Issue Date: September 2010

Abstract


A simple and highly efficient protocol for the synthesis of quinoxaline derivatives from various ortho-phenylenediamines with α-halo ketones under catalyst free conditions is reported by using polyethylene glycol (PEG-400) as an efficient recyclable medium without using any organic co-solvent or additive. This protocol gives wide range of quinoxaline derivatives with high yields.

1_3_228_231_800


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Keywords


α-Halo ketones; o-Phenylenediamines; Quinoxalines; Catalyst-free; Polyethylene glycol; PEG-400

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DOI: 10.5155/eurjchem.1.3.228-231.172

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Citations

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[4]. F. Hafeez, A. F. Zahoor, M. Irfan, S. Kamal, S. Ahmad
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[21]. Mohsen Abbasi
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[22]. Babita Tanwar, Priyank Purohit, Banothu Naga Raju, Dinesh Kumar, Damodara N. Kommi, Asit K. Chakraborti
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[25]. Rezvan Kardooni, Ali Reza Kiasat
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[27]. Olayinka Oyewale Ajani
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[28]. Yumiko Suzuki, Ren Takehara, Kasumi Miura, Ryota Ito, Noriyuki Suzuki
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How to cite


Nagarapu, L.; Mallepalli, R.; Arava, G.; Yeramanchi, L. Eur. J. Chem. 2010, 1(3), 228-231. doi:10.5155/eurjchem.1.3.228-231.172
Nagarapu, L.; Mallepalli, R.; Arava, G.; Yeramanchi, L. Polyethylene glycol (PEG-400) mediated synthesis of quinoxalines. Eur. J. Chem. 2010, 1(3), 228-231. doi:10.5155/eurjchem.1.3.228-231.172
Nagarapu, L., Mallepalli, R., Arava, G., & Yeramanchi, L. (2010). Polyethylene glycol (PEG-400) mediated synthesis of quinoxalines. European Journal of Chemistry, 1(3), 228-231. doi:10.5155/eurjchem.1.3.228-231.172
Nagarapu, Lingaiah, Raghu Mallepalli, Glory Arava, & Lingappa Yeramanchi. "Polyethylene glycol (PEG-400) mediated synthesis of quinoxalines." European Journal of Chemistry [Online], 1.3 (2010): 228-231. Web. 10 Dec. 2023
Nagarapu, Lingaiah, Mallepalli, Raghu, Arava, Glory, AND Yeramanchi, Lingappa. "Polyethylene glycol (PEG-400) mediated synthesis of quinoxalines" European Journal of Chemistry [Online], Volume 1 Number 3 (29 September 2010)

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