European Journal of Chemistry 2018, 9(3), 236-240 | doi: https://doi.org/10.5155/eurjchem.9.3.236-240.1732 | Get rights and content






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Eco-friendly and simple synthesis of some non-natural flavones through chalcones


Mohammad Saidur Rahman (1) orcid , Sayeda Shakila Alam (2) orcid , Kamrunnahar Happy (3) orcid , Mohammad Mamun Hossain (4) orcid , Mohammad Khademul Islam (5,*) orcid , Foni Bushon Biswas (6) orcid

(1) Department of Chemistry, Faculty of Mathematical and Physical Sciences, Jahangirnagar University, Savar, Dhaka-1342, Bangladesh
(2) Department of Chemistry, Faculty of Mathematical and Physical Sciences, Jahangirnagar University, Savar, Dhaka-1342, Bangladesh
(3) Department of Chemistry, Faculty of Mathematical and Physical Sciences, Jahangirnagar University, Savar, Dhaka-1342, Bangladesh
(4) Department of Chemistry, Faculty of Mathematical and Physical Sciences, Jahangirnagar University, Savar, Dhaka-1342, Bangladesh
(5) Department of Chemistry, Faculty of Science, Mawlana Bhashani Science and Technology University, Santosh, Tangail-1902, Bangladesh
(6) Department of Chemistry, Faculty of Science, University of Chittagong, Chittagong-4331, Bangladesh
(*) Corresponding Author

Received: 08 May 2018 | Revised: 04 Jun 2018 | Accepted: 06 Jun 2018 | Published: 30 Sep 2018 | Issue Date: September 2018

Abstract


A distinctive feature of polyphenolics is the possession of biological properties such as antioxidant and antimicrobial activities. Simple synthesis and study about such important class of compounds and their analogs are very important to enhance the understanding of their role in human health and diseases. Accordingly, a series of chalcones (2a-f) have been synthesized by Claisen-Schmidt condensation reaction with required acetophenones and aromatic aldehydes in high yields. The conversion of chalcones to the corresponding flavones (1a-g) taking minimal amount of dimethyl sulfoxide with iodine in presence of sulfuric acid was carried out under microwave conditions in high yields.


Keywords


Iodine; Flavones; Chalcones; Sulfuric acid; Microwave chemistry; Conventional synthesis

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DOI: 10.5155/eurjchem.9.3.236-240.1732

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Funding information


The Ministry of Science and Technology, Government of the People’s Republic of Bangladesh.

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How to cite


Rahman, M.; Alam, S.; Happy, K.; Hossain, M.; Islam, M.; Biswas, F. Eur. J. Chem. 2018, 9(3), 236-240. doi:10.5155/eurjchem.9.3.236-240.1732
Rahman, M.; Alam, S.; Happy, K.; Hossain, M.; Islam, M.; Biswas, F. Eco-friendly and simple synthesis of some non-natural flavones through chalcones. Eur. J. Chem. 2018, 9(3), 236-240. doi:10.5155/eurjchem.9.3.236-240.1732
Rahman, M., Alam, S., Happy, K., Hossain, M., Islam, M., & Biswas, F. (2018). Eco-friendly and simple synthesis of some non-natural flavones through chalcones. European Journal of Chemistry, 9(3), 236-240. doi:10.5155/eurjchem.9.3.236-240.1732
Rahman, Mohammad, Sayeda Shakila Alam, Kamrunnahar Happy, Mohammad Mamun Hossain, Mohammad Khademul Islam, & Foni Bushon Biswas. "Eco-friendly and simple synthesis of some non-natural flavones through chalcones." European Journal of Chemistry [Online], 9.3 (2018): 236-240. Web. 19 Sep. 2020
Rahman, Mohammad, Alam, Sayeda, Happy, Kamrunnahar, Hossain, Mohammad, Islam, Mohammad, AND Biswas, Foni. "Eco-friendly and simple synthesis of some non-natural flavones through chalcones" European Journal of Chemistry [Online], Volume 9 Number 3 (30 September 2018)

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DOI Link: https://doi.org/10.5155/eurjchem.9.3.236-240.1732

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