European Journal of Chemistry

Hydrogen bonding framework in imidazole derivatives: Crystal structure and Hirshfeld surface analysis

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Published: Mar 31, 2020
DOI: https://doi.org/10.5155/eurjchem.11.1.50-59.1945
Keywords:
Synthesis, Crystal structure, Hydrogen bonding, Imidazole derivative, Hirshfeld surface analysis, Intermolecular interactions
Section
Research Article
Issue
Vol. 11 No. 1 (2020): March 2020
Dates
Received 2019-12-12
Accepted 2020-01-28
Published 2020-03-31
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Praveen Singh
Department of Chemistry, Centre of Advance Studies, Institute of Science, Banaras Hindu University, Varanasi 221005, India
http://orcid.org/0000-0002-4740-3152
Ranjeet Kumar
Department of Chemistry, Chaudhary Mahadeo Prasad Degree College, Allahabad, 211002, India
http://orcid.org/0000-0003-1808-2473
Ashish Kumar Tewari
Department of Chemistry, Centre of Advance Studies, Institute of Science, Banaras Hindu University, Varanasi 221005, India
http://orcid.org/0000-0002-1388-5843

Abstract

A series of imidazole derivatives (1-3) were synthesized with three component reaction among benzil, ammonium acetate and formaldehyde/aromatic aldehyde at 110 °C without a catalyst and solvent. These synthesized imidazole derivatives have shown intermolecular hydrogen bonding such as N-H···N and O-H···N. The imidazole 1 and 2 exhibited N-H···N intermolecular hydrogen bonding while imidazole 3 exhibited O-H···N intermolecular hydrogen bonding. The hydrogen bonds in imidazoles were studied by X-ray crystallography and Hirshfeld Surface Analysis at dnorm surface which show the visible red spots, indicated for hydrogen bonds. Further, Hirshfeld surface analysis also shows the percentage of all intermolecular interactions.


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Singh, P.; Kumar, R.; Tewari, A. K. Hydrogen Bonding Framework in Imidazole Derivatives: Crystal Structure and Hirshfeld Surface Analysis. Eur. J. Chem. 2020, 11, 50-59.

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Supporting Agencies

University Grant Commission (Grant Sanction No. 37-54/2009), India, Department of Chemistry, Banaras Hindu University, Varanasi, India.
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