European Journal of Chemistry 2021, 12(1), 18-22 | doi: https://doi.org/10.5155/eurjchem.12.1.18-22.2036 | Get rights and content

Issue cover




Crossmark

  Open Access OPEN ACCESS | Open Access PEER-REVIEWED | RESEARCH ARTICLE | DOWNLOAD PDF | VIEW FULL-TEXT PDF | TOTAL VIEWS

Quick and simultaneous determination of caffeine and taurine in beverages using UPLC-ESI-MS


Mohd Aftab Alam (1,*) orcid , Rayan Saud Al-Arifi (2) orcid , Abdulaziz Abdullah Al-Qarni (3) orcid , Abdullah Shaya Al-Dosseri (4) orcid , Fahad Ibrahim Al-Jenoobi (5) orcid

(1) Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, 11451, The Kingdom of Saudi Arabia
(2) Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, 11451, The Kingdom of Saudi Arabia
(3) Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, 11451, The Kingdom of Saudi Arabia
(4) Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, 11451, The Kingdom of Saudi Arabia
(5) Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, 11451, The Kingdom of Saudi Arabia
(*) Corresponding Author

Received: 26 Aug 2020 | Revised: 11 Oct 2020 | Accepted: 07 Dec 2020 | Published: 31 Mar 2021 | Issue Date: March 2021

Abstract


A rapid UPLC-ESI-MS method was developed for simultaneous determination of caffeine and taurine in beverages (energy drinks and soft drinks). The molecular ions of caffeine and taurine were identified in single ion recording mode at m/z 194.98 and 125.86, respectively. The mass spectrometer parameters were optimized as: capillary voltage 3.0 kV, cone voltage 35 V, extractor 3 V, RF Lens 0.1 V, source temperature 150 °C, desolvation temperature 350 °C, nitrogen 600 L/h, LMR1 7.9, HMR1 15.2, IE1 0.30. The mobile phase comprising methanol (0.1% formic acid) (A) and water (5 mM ammonium acetate) (B) was used in gradient mode. The mobile phase components A and B were pumped in 80:20 (v:v) ratio from 0-0.44 min, and then 100% of component A was pumped between 0.45-0.68 min, and at 0.69 min the composition was returned to 80:20 (v:v) ratio of A and B till 2.0 min. Caffeine and taurine were eluted at 0.46 and 0.43 min, respectively. The samples of energy drinks and soft drinks were diluted in a solvent system comprising methanol and water in 80:20 (v:v) ratio. Our investigations showed that soft drinks SD1 and SD2 have 88.8±4.2% and 110.7±3.6% (w:w) caffeine of their labeled claim. The caffeine content in energy drink brands ED1, ED2, ED3, and ED4 was 76.9±2.5, 65.6±3.4, 88.1±12.6, and 89.1±2.8% (w:w) of labeled claims, respectively. While taurine content in ED1, ED2, ED3, and ED4 was 86.5±8.4, 81.3±27.5, 101.9±4.8, and 97.1±0.3% (w:w) of labeled claim, respectively.


Keywords


Taurine; Caffeine; Soft drinks; UPLC-ESI-MS; Energy drinks; Simultaneous determination

Full Text:

PDF
PDF    Open Access

DOI: 10.5155/eurjchem.12.1.18-22.2036

Links for Article


| | | | | | |

| | | | | | |

| | | |

Related Articles




Article Metrics

icon graph This Abstract was viewed 343 times | icon graph PDF Article downloaded 95 times

Funding information


Research Center of College of Pharmacy and Deanship of Scientific Research, King Saud University, Riyadh, 11451, The Kingdom of Saudi Arabia

Citations

/


[1]. Drita Abazi, Nora Limani-Bektashi, Olga Popovska
Development of thin-layer chromatographic method for determination of caffeine in black, green, and white tea
European Journal of Chemistry  12(3), 284, 2021
DOI: 10.5155/eurjchem.12.3.284-288.2131
/


References


[1]. Souza, D. B.; Del Coso, J.; Casonatto, J.; Polito, M. D. Eur. J. Nutr. 2017, 56 (1), 13-27.
https://doi.org/10.1007/s00394-016-1331-9

[2]. Mets, M. A.; Ketzer, S.; Blom, C.; van Gerven, M. H.; van Willigenburg, G. M.; Olivier, B.; Verster, J. C. Psychopharmacology (Berl). 2011, 214 (3), 737-745.
https://doi.org/10.1007/s00213-010-2078-2

[3]. Lalanne, L.; Lutz, P. E.; Paille, F. Prog. Neuropsychopharmacol. Biol. Psychiatry 2017, 76, 188-194.
https://doi.org/10.1016/j.pnpbp.2017.03.007

[4]. Sanchis-Gomar, F.; Pareja-Galeano, H.; Cervellin, G.; Lippi, G.; Earnest, C. P. Can. J. Cardiol. 2015, 31 (5), 572-575.
https://doi.org/10.1016/j.cjca.2014.12.019

[5]. Petit, A.; Karila, L.; Lejoyeux, M. Presse. Med. 2015, 44 (3), 261-270.
https://doi.org/10.1016/j.lpm.2014.07.029

[6]. Avci, S.; Sarikaya, R.; Buyukcam, F. Am. J. Emerg. Med. 2013, 31 (11), 1624. e3-4.
https://doi.org/10.1016/j.ajem.2013.06.031

[7]. Gray, B.; Ingles, J.; Medi, C.; Driscoll, T.; Semsarian, C. Int. J. Cardiol. 2017, 231, 150-154.
https://doi.org/10.1016/j.ijcard.2016.12.019

[8]. Giles, G. E.; Mahoney, C. R.; Brunye, T. T.; Gardony, A. L.; Taylor, H. A.; Kanarek, R. B. Pharmacol. Biochem. Behav. 2012, 102 (4), 569-577.
https://doi.org/10.1016/j.pbb.2012.07.004

[9]. Aranda, M.; Morlock, G. J. Chromatogr. A. 2006, 1131 (1-2), 253-260.
https://doi.org/10.1016/j.chroma.2006.07.018

[10]. Racz, A.; Heberger, K.; Fodor, M. Anal. Bioanal. Chem. 2016, 408 (23), 6403-6411.
https://doi.org/10.1007/s00216-016-9757-8

[11]. Russo, M.; Dugo, P.; Fanali, C.; Dugo, L.; Zoccali, M.; Mondello, L.; De Gara, L. Food Anal. Methods. 2018, 11 (10), 2637-2644.
https://doi.org/10.1007/s12161-018-1247-5

[12]. Triebel, S.; Sproll, C.; Reusch, H.; Godelmann, R.; Lachenmeier, D. W. Amino Acids 2007, 33 (3), 451-457.
https://doi.org/10.1007/s00726-006-0449-0

[13]. Vochyanova, B.; Opekar, F.; Tuma, P. Electrophoresis 2014, 35 (11), 1660-1665.
https://doi.org/10.1002/elps.201300480

[14]. Draganov, G. B.; Pencheva, I. P.; Todorova, K. A. Int. J. Food Sci. Nutr. 2014, 3 (2), 123-126.

[15]. Chirita, R. I.; Dascalu, C.; Gavrila, L.; Elfakir, C. Rev. Chim. (Bucharest). 2010, 61 (12), 1173-1176.
https://doi.org/10.1176/ps.2010.61.12.1173

[16]. Ricciutelli, M.; Caprioli, G.; Cortese, M.; Lombardozzi, A.; Strano, M.; Vittori, S.; Sagratini, G. J. Chromatogr. A 2014, 1364, 303-307.
https://doi.org/10.1016/j.chroma.2014.08.083

[17]. Al-Bratty, M.; Alhazmi, H. A.; Rehman, Z.; Javed, S. A.; Ahsan, W.; Najmi, A.; Khuwaja, G.; Makeen, H. A.; Khalid, A. J. Spectrosc. (Hindawi). 2020, 2020, Article ID 3716343,
https://doi.org/10.1155/2020/3716343

[18]. Ehlen, L. A.; Marshall, T. A.; Qian, F.; Wefel, J. S.; Warren, J. J. Nutr. Res. 2008, 2 8(5), 299-303.
https://doi.org/10.1016/j.nutres.2008.03.001

[19]. Owens, B. M.; Kitchens, M. J. Contemp. Dent. Pract. 2007, 8 (7), 11-20.
https://doi.org/10.5005/jcdp-8-7-11

[20]. Reddy, A.; Norris, D. F.; Momeni, S. S.; Waldo, B.; Ruby, J. D. J. Am. Dent. Assoc. 2016, 147 (4), 255-263.
https://doi.org/10.1016/j.adaj.2015.10.019


How to cite


Alam, M.; Al-Arifi, R.; Al-Qarni, A.; Al-Dosseri, A.; Al-Jenoobi, F. Eur. J. Chem. 2021, 12(1), 18-22. doi:10.5155/eurjchem.12.1.18-22.2036
Alam, M.; Al-Arifi, R.; Al-Qarni, A.; Al-Dosseri, A.; Al-Jenoobi, F. Quick and simultaneous determination of caffeine and taurine in beverages using UPLC-ESI-MS. Eur. J. Chem. 2021, 12(1), 18-22. doi:10.5155/eurjchem.12.1.18-22.2036
Alam, M., Al-Arifi, R., Al-Qarni, A., Al-Dosseri, A., & Al-Jenoobi, F. (2021). Quick and simultaneous determination of caffeine and taurine in beverages using UPLC-ESI-MS. European Journal of Chemistry, 12(1), 18-22. doi:10.5155/eurjchem.12.1.18-22.2036
Alam, Mohd, Rayan Saud Al-Arifi, Abdulaziz Abdullah Al-Qarni, Abdullah Shaya Al-Dosseri, & Fahad Ibrahim Al-Jenoobi. "Quick and simultaneous determination of caffeine and taurine in beverages using UPLC-ESI-MS." European Journal of Chemistry [Online], 12.1 (2021): 18-22. Web. 27 Oct. 2021
Alam, Mohd, Al-Arifi, Rayan, Al-Qarni, Abdulaziz, Al-Dosseri, Abdullah, AND Al-Jenoobi, Fahad. "Quick and simultaneous determination of caffeine and taurine in beverages using UPLC-ESI-MS" European Journal of Chemistry [Online], Volume 12 Number 1 (31 March 2021)

The other citation formats (EndNote | Reference Manager | ProCite | BibTeX | RefWorks) for this article can be found online at: How to cite item



DOI Link: https://doi.org/10.5155/eurjchem.12.1.18-22.2036

CrossRef | Scilit | GrowKudos | Researchgate | Publons | Microsoft | scibey | Scite | Lens | OUCI

WorldCat Paperbuzz | LibKey Citeas | Dimensions | Semanticscholar | Plumx | Kopernio | Zotero | Mendeley

ZoteroSave to Zotero MendeleySave to Mendeley



European Journal of Chemistry 2021, 12(1), 18-22 | doi: https://doi.org/10.5155/eurjchem.12.1.18-22.2036 | Get rights and content

Refbacks

  • There are currently no refbacks.




Copyright (c) 2021 Authors

Creative Commons License
This work is published and licensed by Atlanta Publishing House LLC, Atlanta, GA, USA. The full terms of this license are available at http://www.eurjchem.com/index.php/eurjchem/pages/view/terms and incorporate the Creative Commons Attribution-Non Commercial (CC BY NC) (International, v4.0) License (http://creativecommons.org/licenses/by-nc/4.0). By accessing the work, you hereby accept the Terms. This is an open access article distributed under the terms and conditions of the CC BY NC License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited without any further permission from Atlanta Publishing House LLC (European Journal of Chemistry). No use, distribution or reproduction is permitted which does not comply with these terms. Permissions for commercial use of this work beyond the scope of the License (http://www.eurjchem.com/index.php/eurjchem/pages/view/terms) are administered by Atlanta Publishing House LLC (European Journal of Chemistry).



© Copyright 2010 - 2021  Atlanta Publishing House LLC All Right Reserved.

The opinions expressed in all articles published in European Journal of Chemistry are those of the specific author(s), and do not necessarily reflect the views of Atlanta Publishing House LLC, or European Journal of Chemistry, or any of its employees.

Copyright 2010-2021 Atlanta Publishing House LLC. All rights reserved. This site is owned and operated by Atlanta Publishing House LLC whose registered office is 2850 Smith Ridge Trce Peachtree Cor GA 30071-2636, USA. Registered in USA.