European Journal of Chemistry 2021, 12(1), 56-59 | doi: https://doi.org/10.5155/eurjchem.12.1.56-59.2070 | Get rights and content

Issue cover




Crossmark

  Open Access OPEN ACCESS | Open Access PEER-REVIEWED | RESEARCH ARTICLE | DOWNLOAD PDF | VIEW FULL-TEXT PDF | TOTAL VIEWS

Synthesis, characterization, and antimicrobial activity of 4-imidazolecarboxaldehyde thiosemicarbazone and its Pt(II) and Pd(II) complexes


Mohammed Bahreldin Hussein (1) orcid , Muna Mahdi Mohammed (2) orcid , Abdalla Gobara (3,*) orcid , Asha Fadllallah Wady (4) orcid , Awad Salim Ibrahim Holy (5) orcid

(1) Department of Chemistry, Faculty of Science, University of Kordofan, Elobeid, 52211, Sudan
(2) Department of Chemistry, Faculty of Science, University of Kordofan, Elobeid, 52211, Sudan
(3) Department of Chemistry, Faculty of Education, Dalanj University, Dalanj, 53312 Sudan
(4) Department of Chemistry, Faculty of Science, University of Kordofan, Elobeid, 52211, Sudan
(5) Department of Chemistry, Faculty of Education, West Kordofan University, El-Nuhud, 55511, Sudan
(*) Corresponding Author

Received: 15 Jan 2021 | Revised: 14 Feb 2021 | Accepted: 18 Feb 2021 | Published: 31 Mar 2021 | Issue Date: March 2021

Abstract


Schiff bases are versatile ligands, synthesized via condensation of primary amines with carbonyl compounds. In this study, equimolar amounts of 4-imidazolecarboxaldehyde and thiosemicarbazide were combined and the Schiff base 4-imidazolecarboxaldehyde thiosemicarbazone was prepared as a new bidentate complexing agent. The synthesized ligand was reacted with palladium (II) and platinum (II) ions yielding air-stable complexes. For characterization purpose, infrared spectra, mass spectra, electronic spectra, thermal analysis, proton nuclear magnetic resonance and 13-carbon nuclear magnetic resonance spectra studies were carried out on the obtained complexes and ligand. The characterization data showed that the ligand acts as a bidentate coordinate to the metal ions through azomethine nitrogen and sulfur atoms. An in vitro antimicrobial investigation was also carried out for the free ligand and its metal complexes against four bacteria; Bacillus cereus, Staphylococcus aureus (Gram-positive), Escherichia coli and Salmonella typhimurium (Gram-negative) and one Fungi; Candida albicans, to assess their antimicrobial properties by disc diffusion technique. Antimicrobial activity of the prepared complexes showed higher activity than the free ligand.


Announcements


Our editors have decided to support scientists to publish their manuscripts in European Journal of Chemistry without any financial constraints.

1- The article processing fee will not be charged from the articles containing the single-crystal structure characterization or a DFT study between September 15, 2023 and October 31, 2023 (Voucher code: FALL2023).

2. A 50% discount will be applied to the article processing fee for submissions made between September 15, 2023 and October 31, 2023 by authors who have at least one publication in the European Journal of Chemistry (Voucher code: AUTHOR-3-2023).

3. Young writers will not be charged for the article processing fee between September 15, 2023 and October 31, 2023 (Voucher code: YOUNG2023).

Editor-in-Chief
European Journal of Chemistry

Keywords


Synthesis; Schiff base; Antimicrobial activity; Structural characterization; Pd(II) and Pt(II) complexes; Imidazole thiosemicarbazone

Full Text:

PDF
PDF    Open Access

DOI: 10.5155/eurjchem.12.1.56-59.2070

Links for Article


| | | | | | |

| | | | | | |

| | | |

Related Articles




Article Metrics

icon graph This Abstract was viewed 920 times | icon graph PDF Article downloaded 436 times

Funding information


Department of Inorganic Chemistry, Technical University of Dresden, Germany.

Citations

/


[1]. Ilaria D’Agostino, Githa Elizabeth Mathew, Paola Angelini, Roberto Venanzoni, Giancarlo Angeles Flores, Andrea Angeli, Simone Carradori, Beatrice Marinacci, Luigi Menghini, Mohamed A. Abdelgawad, Mohammed M. Ghoneim, Bijo Mathew, Claudiu T. Supuran
Biological investigation of N-methyl thiosemicarbazones as antimicrobial agents and bacterial carbonic anhydrases inhibitors
Journal of Enzyme Inhibition and Medicinal Chemistry  37(1), 986, 2022
DOI: 10.1080/14756366.2022.2055009
/

References


[1]. Quiroga, A. G.; Perez, J. M.; Lopez-Solera, I.; Masaguer, J. R.; Luque, A.; Roman, P.; Edwards, A.; Alonso, C.; Navarro-Ranninger, C. J. Med. Chem. 1998, 41 (9), 1399-1408.
https://doi.org/10.1021/jm970520d

[2]. Agarwal, R. K.; Singh, L.; Sharma, D. K. Bioinorg. Chem. Appl. 2006, 2006, 1-10.

[3]. Kovala-Demertzi, D.; Varadinova, T.; Genova, P.; Souza, P.; Demertzis, M. A. Bioinorg. Chem. Appl. 2007, 2007, 1-6.
https://doi.org/10.1155/2007/56165

[4]. Scovill, J. P.; Klayman, D. L.; Franchino, C. F. J. Med. Chem. 1982, 25 (10), 1261-1264.
https://doi.org/10.1021/jm00352a036

[5]. Costa, R. F. F.; Rebolledo, A. P.; Matencio, T.; Calado, H. D. R.; Ardisson, J. D.; Cortes, M. E.; Rodrigues, B. L.; Beraldo, H. J. Coord. Chem. 2005, 58 (15), 1307-1319.
https://doi.org/10.1080/00958970500213307

[6]. Pandey, O. P.; Sengupta, S. K.; Mishra, M. K.; Tripathi, C. M. Bioinorg. Chem. Appl. 2003, 1 (1), 35-44.
https://doi.org/10.1155/S1565363303000037

[7]. Kovala-Demertzi, D.; Boccarelli, A.; Demertzis, M. A.; Coluccia, M. Chemotherapy 2007, 53 (2), 148-152.
https://doi.org/10.1159/000099986

[8]. Shipman, C., Jr.; Smith, S. H.; Drach, J. C.; Klayman, D. L. Antiviral Res. 1986, 6 (4), 197-222.
https://doi.org/10.1016/0166-3542(86)90002-1

[9]. Lobana, T. S.; Casas, J. S.; Castineiras, A.; Garcia-Tasende, M. S.; Sanchez, A.; Sordo, J. Inorg. Chim. Acta 2003, 347, 23-32.
https://doi.org/10.1016/S0020-1693(02)01433-0

[10]. Hernandez, W.; Paz, J.; Vaisberg, A.; Spodine, E.; Richter, R.; Beyer, L. Bioinorg. Chem. Appl. 2008, 2008, 1-9.
https://doi.org/10.1155/2008/690952

[11]. Pingaew, R.; Prachayasittikul, S.; Ruchirawat, S. Molecules 2010, 15 (2), 988-996.
https://doi.org/10.3390/molecules15020988

[12]. Haraguchi, S. K.; Silva, A. A.; Vidotti, G. J.; Dos Santos, P. V.; Garcia, F. P.; Pedroso, R. B.; Nakamura, C. V.; De Oliveira, C. M. A.; Da Silva, C. C. Molecules 2011, 16 (2), 1166-1180.
https://doi.org/10.3390/molecules16021166

[13]. Deschamps, P.; Kulkarni, P. P.; Sarkar, B. Inorg. Chem. 2003, 42 (23), 7366-7368.
https://doi.org/10.1021/ic034760x

[14]. Sigel, H.; Saha, A.; Saha, N.; Carloni, P.; Kapinos, L. E.; Griesser, R. J. Inorg. Biochem. 2000, 78 (2), 129-137.
https://doi.org/10.1016/S0162-0134(99)00219-6

[15]. Russell, Hugo and Ayliffe's Principles and Practice of Disinfection, Preservation and Sterilization, Fraise, A. P., Maillard, J. Y., Sattar, S. A., Eds.; 5th Edition; Wiley-Blackwell, 2013.

[16]. West, D. X.; Lockwood, M. A.; Albert, J. N.; Liberta, A. E. Spectrochim. Acta A 1993, 49 (12), 1809-1816.
https://doi.org/10.1016/0584-8539(93)80250-E

[17]. Casas, J. S.; Castineiras, A.; Rodriguez-Argüelles, M. C.; Sanchez, A.; Sordo, J.; Vazquez-Lopez, A.; Vazquez-Lopez, E. M. J. Chem. Soc., Dalton Trans. 2000, 14, 2267-2272.
https://doi.org/10.1039/b002286l

[18]. Rodriguez-Arguelles, M. C.; Lopez-Silva, E. C.; Sanmartin, J.; Bacchi, A.; Pelizzi, C.; Zani, F. Inorg. Chim. Acta 2004, 357 (9), 2543-2552.
https://doi.org/10.1016/j.ica.2004.02.013

[19]. Houari, B.; Louhibi, S.; Boukli-Hacene, L.; Roisnel, T.; Taleb, M. Acta Cryst. E 2013, 69 (9), o1469-o1469.
https://doi.org/10.1107/S1600536813022927

[20]. Reis, D.; Despaigne, A.; Silva, J.; Silva, N.; Vilela, C.; Mendes, I.; Takahashi, J.; Beraldo, H. Molecules 2013, 18 (10), 12645-12662.
https://doi.org/10.3390/molecules181012645

[21]. Gobara, A. G. H., PhD Thesis, Synthesis, Characterization and Biological Activity of Some Thiosemicarbazone Ligands and their Complexes with Some M (II) ions, University of Gezira, 2017.

[22]. Tyagi, M.; Chandra, S. Open J. Inorg. Chem. 2012, 2 (3), 41-48.
https://doi.org/10.4236/ojic.2012.23007

[23]. Sapna, K.; Sharma, N. K.; Kohli, S. Orient. J. Chem. 2012, 28 (2), 969-974.
https://doi.org/10.13005/ojc/280244

[24]. Gujarathi, J. R.; Pawar, N. S.; Bendre. R. S. J. Chem. Pharm. Res. 2013, 5 (7), 161-168.

[25]. Mendes, I. C.; Moreira, J. P.; Speziali, N. L.; Mangrich, A. S.; Takahashi, J. A.; Beraldo, H. J. Braz. Chem. Soc. 2006, 17 (8), 1571-1577.
https://doi.org/10.1590/S0103-50532006000800013

[26]. Chandra, S.; Singh, G.; Tyagi, V. P.; Raizada, S. Synth. React. Inorg. Metal-Org. Chem. 2001, 31 (10), 1759-1769.
https://doi.org/10.1081/SIM-100108260

[27]. Al-Kubaisi, A. H. Bull. Korean Chem. Soc. 2004, 25 (1), 37-41

[28]. Bingol, H.; Coskun, A.; Akgemci, E. G.; Kaya, B.; Atalay, T. Chin. J. Chem. 2007, 25 (3), 307-311.
https://doi.org/10.1002/cjoc.200790060


How to cite


Hussein, M.; Mohammed, M.; Gobara, A.; Wady, A.; Holy, A. Eur. J. Chem. 2021, 12(1), 56-59. doi:10.5155/eurjchem.12.1.56-59.2070
Hussein, M.; Mohammed, M.; Gobara, A.; Wady, A.; Holy, A. Synthesis, characterization, and antimicrobial activity of 4-imidazolecarboxaldehyde thiosemicarbazone and its Pt(II) and Pd(II) complexes. Eur. J. Chem. 2021, 12(1), 56-59. doi:10.5155/eurjchem.12.1.56-59.2070
Hussein, M., Mohammed, M., Gobara, A., Wady, A., & Holy, A. (2021). Synthesis, characterization, and antimicrobial activity of 4-imidazolecarboxaldehyde thiosemicarbazone and its Pt(II) and Pd(II) complexes. European Journal of Chemistry, 12(1), 56-59. doi:10.5155/eurjchem.12.1.56-59.2070
Hussein, Mohammed, Muna Mahdi Mohammed, Abdalla Gobara, Asha Fadllallah Wady, & Awad Salim Ibrahim Holy. "Synthesis, characterization, and antimicrobial activity of 4-imidazolecarboxaldehyde thiosemicarbazone and its Pt(II) and Pd(II) complexes." European Journal of Chemistry [Online], 12.1 (2021): 56-59. Web. 10 Dec. 2023
Hussein, Mohammed, Mohammed, Muna, Gobara, Abdalla, Wady, Asha, AND Holy, Awad. "Synthesis, characterization, and antimicrobial activity of 4-imidazolecarboxaldehyde thiosemicarbazone and its Pt(II) and Pd(II) complexes" European Journal of Chemistry [Online], Volume 12 Number 1 (31 March 2021)

The other citation formats (EndNote | Reference Manager | ProCite | BibTeX | RefWorks) for this article can be found online at: How to cite item



DOI Link: https://doi.org/10.5155/eurjchem.12.1.56-59.2070


CrossRef | Scilit | GrowKudos | Researchgate | Publons | ScienceGate | Scite | Lens | OUCI

WorldCat Paperbuzz | LibKey Citeas | Dimensions | Semanticscholar | Plumx | Kopernio | Zotero | Mendeley

ZoteroSave to Zotero MendeleySave to Mendeley



European Journal of Chemistry 2021, 12(1), 56-59 | doi: https://doi.org/10.5155/eurjchem.12.1.56-59.2070 | Get rights and content

Refbacks

  • There are currently no refbacks.


Bookmark and Share


Copyright (c) 2021 Authors

Creative Commons License
This work is published and licensed by Atlanta Publishing House LLC, Atlanta, GA, USA. The full terms of this license are available at http://www.eurjchem.com/index.php/eurjchem/pages/view/terms and incorporate the Creative Commons Attribution-Non Commercial (CC BY NC) (International, v4.0) License (http://creativecommons.org/licenses/by-nc/4.0). By accessing the work, you hereby accept the Terms. This is an open access article distributed under the terms and conditions of the CC BY NC License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited without any further permission from Atlanta Publishing House LLC (European Journal of Chemistry). No use, distribution or reproduction is permitted which does not comply with these terms. Permissions for commercial use of this work beyond the scope of the License (http://www.eurjchem.com/index.php/eurjchem/pages/view/terms) are administered by Atlanta Publishing House LLC (European Journal of Chemistry).


© Copyright 2010 - 2023 • Atlanta Publishing House LLC • All Right Reserved.

The opinions expressed in all articles published in European Journal of Chemistry are those of the specific author(s), and do not necessarily reflect the views of Atlanta Publishing House LLC, or European Journal of Chemistry, or any of its employees.

Copyright 2010-2023 Atlanta Publishing House LLC. All rights reserved. This site is owned and operated by Atlanta Publishing House LLC whose registered office is 2850 Smith Ridge Trce Peachtree Cor GA 30071-2636, USA. Registered in USA.