Email this article 
Hide
Show all
OPEN ACCESS | 
PEER-REVIEWED |
RESEARCH ARTICLE
|
DOWNLOAD PDF
|
VIEW FULL-TEXT PDF
| TOTAL VIEWS
Highly efficient fluorescence resonance energy transfer in co-encapsulated BODIPY nanoparticles
Priyadarshine Hewavitharanage (1,*)
, Launa Steele (2) , Isaac Dickenson (3) (1) Department of Chemistry, University of Southern Indiana, Evansville, Indiana 47712, USA
(2) Department of Chemistry, University of Southern Indiana, Evansville, Indiana 47712, USA
(3) Department of Chemistry, University of Southern Indiana, Evansville, Indiana 47712, USA
(*) Corresponding Author
Received: 18 Jul 2021 | Revised: 20 Aug 2021 | Accepted: 28 Aug 2021 | Published: 31 Dec 2021 | Issue Date: December 2021
Abstract
Fluorescence resonance energy transfer (FRET) is a powerful tool used in a wide range of applications due to its high sensitivity and many other advantages. Co-encapsulation of a donor and an acceptor in nanoparticles is a useful strategy to bring the donor-acceptor pair in proximity for FRET. A highly efficient FRET system based on BODIPY-BODIPY (BODIPY: boron-dipyrromethene) donor-acceptor pair in nanoparticles was synthesized. Nanoparticles were formed by co-encapsulating a green emitting BODIPY derivative (FRET donor, lmax = 501 nm) and a red emitting BODIPY derivative (FRET acceptor, lmax = 601 nm) in an amphiphilic polymer using the precipitation method. Fluorescence measurements of encapsulated BODIPY in water following 501 nm excitation caused a 3.6 fold enhancement of the acceptor BODIPY emission at 601 nm indicating efficient energy transfer between the green emitting donor BODIPY and the red emitting BODIPY acceptor with a 100 nm Stokes shift. The calculated FRET efficiency was 96.5%. Encapsulated BODIPY derivatives were highly stable under our experimental conditions.
Announcements
Our editors have decided to support scientists to publish their manuscripts in European Journal of Chemistry without any financial constraints.
1- The article processing fee will not be charged from the articles containing the single-crystal structure characterization or a DFT study between September 15, 2023 and October 31, 2023 (Voucher code: FALL2023).
2. A 50% discount will be applied to the article processing fee for submissions made between September 15, 2023 and October 31, 2023 by authors who have at least one publication in the European Journal of Chemistry (Voucher code: AUTHOR-3-2023).
3. Young writers will not be charged for the article processing fee between September 15, 2023 and October 31, 2023 (Voucher code: YOUNG2023).
Editor-in-Chief
European Journal of Chemistry
Keywords
Full Text:
PDF
DOI: 10.5155/eurjchem.12.4.361-367.2155
Links for Article
| | | | | | |
| | | | | | |
| | | |
Related Articles
Article Metrics
This Abstract was viewed 532 times |
PDF Article downloaded 152 times
Funding information
University of Southern Indiana, Evansville, Indiana 47712, USA
References
[1]. Hewavitharanage, P.; Warshawsky, R.; Rosokha, S. V.; Vaal, J.; Stickler, K.; Bachynsky, D.; Jairath, N. Tetrahedron 2020, 76 (42), 131515-131525.
https://doi.org/10.1016/j.tet.2020.131515
[2]. Barin, G.; Yilmaz, M. D.; Akkaya, E. U. Tetrahedron Lett. 2009, 50 (15), 1738-1740.
https://doi.org/10.1016/j.tetlet.2009.01.141
[3]. Sharma, R.; Gobeze, H. B.; D'Souza, F.; Ravikanth, M. ChemPhysChem 2016, 17 (16), 2516-2524.
https://doi.org/10.1002/cphc.201600317
[4]. Sapsford, K. E.; Berti, L.; Medintz, I. L. Angew. Chem. Int. Ed Engl. 2006, 45 (28), 4562-4589.
https://doi.org/10.1002/anie.200503873
[5]. Förster, T. Ann. Phys. 1948, 437 (1-2), 55-75.
https://doi.org/10.1002/andp.19484370105
[6]. Dexter, D. L. J. Chem. Phys. 1953, 21 (5), 836-850.
https://doi.org/10.1063/1.1699044
[7]. Al-Omari, S. J. Biol. Phys. 2016, 42 (3), 373-382.
https://doi.org/10.1002/cbin.10914
[8]. McConnell, H. M. J. Chem. Phys. 1961, 35 (2), 508-515.
https://doi.org/10.1063/1.1731961
[9]. Pourtois, G.; Beljonne, D.; Cornil, J.; Ratner, M. A.; Brédas, J. L. J. Am. Chem. Soc. 2002, 124 (16), 4436-4447.
https://doi.org/10.1021/ja017150+
[10]. Principles of Fluorescence Spectroscopy; Lakowicz, J. R., Ed.; Springer US: Boston, MA, 2006.
[11]. Bhuckory, S.; Kays, J. C.; Dennis, A. M. Biosensors (Basel) 2019, 9 (2), 76-111.
https://doi.org/10.3390/bios9020076
[12]. Chen, G.; Song, F.; Xiong, X.; Peng, X. Ind. Eng. Chem. Res. 2013, 52 (33), 11228-11245.
https://doi.org/10.1021/ie303485n
[13]. Rainey, K. H.; Patterson, G. H. Proc. Natl. Acad. Sci. U. S. A. 2019, 116 (3), 864-873.
https://doi.org/10.1073/pnas.1805333116
[14]. Zohoorian-Abootorabi, T.; Sanee, H.; Iranfar, H.; Saberi, M. R.; Chamani, J. Spectrochim. Acta A Mol. Biomol. Spectrosc. 2012, 88, 177-191.
https://doi.org/10.1016/j.saa.2011.12.026
[15]. Blouin, S.; Craggs, T. D.; Lafontaine, D. A.; Penedo, J. C. Methods Mol. Biol. 2009, 543, 475-502.
https://doi.org/10.1007/978-1-60327-015-1_28
[16]. Gustiananda, M.; Liggins, J. R.; Cummins, P. L.; Gready, J. E. Biophys. J. 2004, 86 (4), 2467-2483.
https://doi.org/10.1016/S0006-3495(04)74303-9
[17]. Yang, J.; Chen, H.; Vlahov, I. R.; Cheng, J.-X.; Low, P. S. Proc. Natl. Acad. Sci. U. S. A. 2006, 103 (37), 13872-13877.
https://doi.org/10.1073/pnas.0601455103
[18]. Liu, Y.; Yang, G.; Jin, S.; Zhang, R.; Chen, P.; Tengjisi; Wang, L.; Chen, D.; Weitz, D. A.; Zhao, C.-X. Angew. Chem. Int. Ed Engl. 2020, 59 (45), 20065-20074.
https://doi.org/10.1002/anie.202008018
[19]. Yuan, L.; Lin, W.; Zheng, K.; Zhu, S. Acc. Chem. Res. 2013, 46 (7), 1462-1473.
https://doi.org/10.1021/ar300273v
[20]. Hu, R.; Zhang, X.; Zhao, Z.; Zhu, G.; Chen, T.; Fu, T.; Tan, W. Angew. Chem. Int. Ed Engl. 2014, 53 (23), 5821-5826.
https://doi.org/10.1002/anie.201400323
[21]. Rajdev, P.; Ghosh, S. J. Phys. Chem. B 2019, 123 (2), 327-342.
https://doi.org/10.1021/acs.jpcb.8b09441
[22]. Saxena, S.; Pradeep, A.; Jayakannan, M. ACS Appl. Bio Mater. 2019, 2 (12), 5245-5262.
https://doi.org/10.1021/acsabm.9b00450
[23]. Benniston, A. C.; Copley, G. Phys. Chem. Chem. Phys. 2009, 11 (21), 4124-4131.
https://doi.org/10.1039/b901383k
[24]. Karolin, J.; Johansson, L. B.-A.; Strandberg, L.; Ny, T. J. Am. Chem. Soc. 1994, 116 (17), 7801-7806.
https://doi.org/10.1021/ja00096a042
[25]. Ziessel, R.; Ulrich, G.; Harriman, A. New J Chem 2007, 31 (4), 496-501.
https://doi.org/10.1039/b617972j
[26]. Ulrich, G.; Ziessel, R.; Harriman, A. Angew. Chem. Int. Ed Engl. 2008, 47 (7), 1184-1201.
https://doi.org/10.1002/anie.200702070
[27]. Patalag, L. J.; Hoche, J.; Holzapfel, M.; Schmiedel, A.; Mitric, R.; Lambert, C.; Werz, D. B. J. Am. Chem. Soc. 2021, 143 (19), 7414-7425.
https://doi.org/10.1021/jacs.1c01279
[28]. Hewavitharanage, P.; Nzeata, P.; Wiggins, J. Eur. J. Chem. 2012, 3 (1), 13-16.
https://doi.org/10.5155/eurjchem.3.1.13-16.543
[29]. Delmotte, C.; Delmas, A. Bioorg. Med. Chem. Lett. 1999, 9 (20), 2989-2994.
https://doi.org/10.1016/S0960-894X(99)00512-0
[30]. Laia, C. A. T.; Costa, S. M. B. Chem. Phys. Lett. 1998, 285 (5-6), 385-390.
https://doi.org/10.1016/S0009-2614(98)00092-X
[31]. Che, W.; Zhang, L.; Li, Y.; Zhu, D.; Xie, Z.; Li, G.; Zhang, P.; Su, Z.; Dou, C.; Tang, B. Z. Anal. Chem. 2019, 91 (5), 3467-3474.
https://doi.org/10.1021/acs.analchem.8b05024
[32]. Hu, W.; Ma, H.; Hou, B.; Zhao, H.; Ji, Y.; Jiang, R.; Hu, X.; Lu, X.; Zhang, L.; Tang, Y.; Fan, Q.; Huang, W. ACS Appl. Mater. Interfaces 2016, 8 (19), 12039-12047.
https://doi.org/10.1021/acsami.6b02721
[33]. Swider, E.; Maharjan, S.; Houkes, K.; van Riessen, N. K.; Figdor, C.; Srinivas, M.; Tagit, O. ACS Appl. Bio Mater. 2019, 2 (3), 1131-1140.
https://doi.org/10.1021/acsabm.8b00754
[34]. Adams, P. G.; Collins, A. M.; Sahin, T.; Subramanian, V.; Urban, V. S.; Vairaprakash, P.; Tian, Y.; Evans, D. G.; Shreve, A. P.; Montano, G. A. Nano Lett. 2015, 15 (4), 2422-2428.
https://doi.org/10.1021/nl504814x
[35]. Galvao, J.; Davis, B.; Tilley, M.; Normando, E.; Duchen, M. R.; Cordeiro, M. F. FASEB J. 2014, 28 (3), 1317-1330.
https://doi.org/10.1096/fj.13-235440
[36]. Takayama, R.; Inoue, Y.; Murata, I.; Kanamoto, I. Colloids interfaces 2020, 4 (3), 28.
https://doi.org/10.3390/colloids4030028
[37]. Hewavitharanage, P. Eur. J. Chem. 2012, 3 (4), 395-398.
https://doi.org/10.5155/eurjchem.3.4.395-398.693
[38]. Warshawsky, R.; Vaal, J.; Hewavitharanage, P. Eur. J. Chem. 2017, 8 (4), 321-327.
https://doi.org/10.5155/eurjchem.8.4.321-327.1634
How to cite
The other citation formats (EndNote | Reference Manager | ProCite | BibTeX | RefWorks) for this article can be found online at: How to cite item
DOI Link: https://doi.org/10.5155/eurjchem.12.4.361-367.2155
| 
| 
| 
| 
| 
| 
| 
| 
| 
| 
| 
| 
| 
| 
| 
Save to Zotero
Save to Mendeley
European Journal of Chemistry 2021, 12(4), 361-367 | doi: https://doi.org/10.5155/eurjchem.12.4.361-367.2155 | Get rights and content
Refbacks
- There are currently no refbacks.
Copyright (c) 2021 Authors
This work is published and licensed by Atlanta Publishing House LLC, Atlanta, GA, USA. The full terms of this license are available at http://www.eurjchem.com/index.php/eurjchem/pages/view/terms and incorporate the Creative Commons Attribution-Non Commercial (CC BY NC) (International, v4.0) License (http://creativecommons.org/licenses/by-nc/4.0). By accessing the work, you hereby accept the Terms. This is an open access article distributed under the terms and conditions of the CC BY NC License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited without any further permission from Atlanta Publishing House LLC (European Journal of Chemistry). No use, distribution or reproduction is permitted which does not comply with these terms. Permissions for commercial use of this work beyond the scope of the License (http://www.eurjchem.com/index.php/eurjchem/pages/view/terms) are administered by Atlanta Publishing House LLC (European Journal of Chemistry).
© Copyright 2010 - 2023 • Atlanta Publishing House LLC • All Right Reserved.
The opinions expressed in all articles published in European Journal of Chemistry are those of the specific author(s), and do not necessarily reflect the views of Atlanta Publishing House LLC, or European Journal of Chemistry, or any of its employees.
Copyright 2010-2023 Atlanta Publishing House LLC. All rights reserved. This site is owned and operated by Atlanta Publishing House LLC whose registered office is 2850 Smith Ridge Trce Peachtree Cor GA 30071-2636, USA. Registered in USA.