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Regioselective synthesis of new 2-(E)-cyano(oxazolidin-2-ylidene)thiazoles
Mehdi Bakavoli (1,*)
, Hamid Beyzaei (2) , Mohammad Rahimizadeh (3) , Hossein Eshghi (4) (1) Department of Chemistry, Faculty of Science, Ferdowsi University of Mashhad, Mashhad, 91375-1436, Iran
(2) Department of Chemistry, Faculty of Science, University of Zabol, Zabol, 98615-538, Iran
(3) Department of Chemistry, Faculty of Science, Ferdowsi University of Mashhad, Mashhad, 91375-1436, Iran
(4) Department of Chemistry, Faculty of Science, Ferdowsi University of Mashhad, Mashhad, 91375-1436, Iran
(*) Corresponding Author
Received: 13 Jan 2011, Accepted: 21 Feb 2011, Published: 30 Sep 2011
Abstract
Reaction of 2-(oxazolidin-2-ylidene)malononitrile (1) with phosphorus pentasulfide gave the corresponding thioamide derivative (2a) in a regioselective manner. Reaction of this compound with several α-bromocarbonyl compounds gave new 2-(E)-cyano(oxazolidin-2-ylidene)thiazoles (3a-g). The chemical structures of novel compounds were confirmed by 1H NMR, elemental analysis, FT-IR spectrometry and mass spectrophotometric analyses.
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DOI: 10.5155/eurjchem.2.3.356-358.389
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[1]. Hamid Beyzaei, Reza Aryan, Zahra Keshtegar
Synthesis of New Imidazolidine and Tetrahydropyrimidine Derivatives
Advances in Chemistry 2014, 1, 2014
DOI: 10.1155/2014/834641
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