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Synthesis, antimicrobial activity and absorption studies of some novel heterocyclic dyes based on 4-hexylbenzene-1,3-diol
Hitendra Mangubhai Patel (1,*)
(1) Department of Chemistry, Vithalbhai Patel and Rajratna Purushotamdas Tulsibhai Patel Science College, Sardar Patel University, Vallabh Vidyanagar, Gujarat, 388120, India
(*) Corresponding Author
Received: 31 Aug 2011 | Revised: 12 Oct 2011 | Accepted: 15 Nov 2011 | Published: 31 Mar 2012 | Issue Date: March 2012
Abstract
Aniline derivatives were diazotized and coupled with 3-aminocrotononitrile to give the corresponding 2-arylhydrazono-3-ketiminobutyronitriles. Cyclization of these arylhydrazono derivatives with hydrazine monohydrate afforded 5-amino-4-arylazo-3-methyl-1H-pyrazoles which were subsequently diazotized and coupled with malononitrile to yield a series of pyrazolylhydrazonomalononitriles. These compounds were then reacted with hydrazine monohydrate to provide, heterocyclic dyes, which were further diazotized and coupled with 4-hexylbenzene-1,3-diol to produce novel heterocyclic tetraazo dyes which were characterized by elemental analysis and spectral methods. The antimicrobial activity and absorption characteristics of the dyes were also examined in detail.
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DOI: 10.5155/eurjchem.3.1.44-50.517
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Colortax Ltd., Surat, India
Citations
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Antimicrobial azo molecules: a review
Journal of the Iranian Chemical Society 18(11), 2829, 2021
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European Journal of Medicinal Chemistry 97, 786, 2015
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DOI Link: https://doi.org/10.5155/eurjchem.3.1.44-50.517
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