

Synthesis of novel 2-propenoyl amides, esters, heterocyclic compounds and their screening as antifungal and antibacterial agents
Ahmed El-Ziaty (1,*)





(1) Chemistry Department, Faculty of Science, Ain Shams University, Abbassia 11566, Cairo, Egypt
(2) Chemistry Department, Faculty of Science, Ain Shams University, Abbassia 11566, Cairo, Egypt
(3) Chemistry Department, Faculty of Science, Ain Shams University, Abbassia 11566, Cairo, Egypt
(4) Chemistry Department, Faculty of Science and Hummanities, Shaqra University, 11962, Harmala, Saudia Arabia
(5) Chemistry Department, Faculty of Science, Ain Shams University, Abbassia 11566, Cairo, Egypt
(*) Corresponding Author
Received: 03 Sep 2011 | Revised: 10 Nov 2011 | Accepted: 26 Sep 2011 | Published: 31 Mar 2012 | Issue Date: March 2012
Abstract
Compound, 2-cyano-3-(2ˊ,4ˊ-dichlorophenyl)-2-prpoenoyl chloride, 3, was reacted with nitrogen, sulfur, and oxygen nucleophilic reagents to give new 2-propenoyl amide and ester derivatives. Some of these derivatives were cyclized under the reaction conditions and/or with POCl3 or Ac2O to give new derivatives of heterocyclic systems. Some of these compounds were tested as antibacterial and antifungal agents.
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DOI: 10.5155/eurjchem.3.1.65-70.518
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Micro Analytical Center, Cairo University, Egypt
Citations
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[2]. Manal M. El-Shahawi, Ahmed K. El-Ziaty
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[3]. Amr M. Abdelmoniem, Said A. S. Ghozlan, Hassan M. Abdelwahab, Ismail A. Abdelhamid
2‐Cyano‐ N ‐(thiophen‐2‐yl)acetamide in Heterocyclic Synthesis: Synthesis and Antibacterial Screening of Novel Pyrido[1,2‐ a ]thieno[3,2‐ e ]pyrimidine‐2‐carboxylate Moieties
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[4]. Amr M. Abdelmoniem, Taher A. Salaheldin, Ismail A. Abdelhamid, Ahmed H. M. Elwahy
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[5]. Naglaa Fawzy, Madeha Othman Ibrahim Ghobashy, Ahmed Kamel El-Ziaty
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[6]. Hanan A. Sallam, Amna S. Elgubbi, Eman A. E. El-Helw
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[7]. Sayed K. Ramadan, Ahmed K. El‐Ziaty, Rania S. Ali
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[8]. Eman A. E. El-Helw, Marwa M. Gado, Ahmed K. El-Ziaty
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