European Journal of Chemistry

Synthesis of some new pyrazolylfuropyrimidinethiones and triazolofuropyrimidinethiones



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Mohamed Abdel Megid Abdel-Hamid
Azza Mohamed Elkazak
Magdy Hamed Sead
Osama Farouk Mohamed

Abstract

Some novel pyrazolylfuropyrimidinethiones were synthesized from cyclocondensation of 4-hydrazino-5,6-diphenylfuro [2,3-d] pyrimidine-2(1H)-thione (3) with different enaminones and 1,3-dicarbonyl compounds. Whereas the furotriazolo-pyrimidinethiones were synthesized from reaction of compound 3 with benzoyl chloride, p-chlorobenzaldehyde and carbon disulphide. Furthermore, furotetrazolo-pyrimidinethione and ditetrazolofuro pyrimidine were synthesized.

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Abdel-Hamid, M. A. M.; Elkazak, A. M.; Sead, M. H.; Mohamed, O. F. Synthesis of Some New Pyrazolylfuropyrimidinethiones and Triazolofuropyrimidinethiones. Eur. J. Chem. 2012, 3, 273-278.

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