Synthesis of some novel benzimidazole derivatives and it's biological evaluation

Doddarasinakere Kempaiah Ravishankara; Paduvalahippe Gowdegowda Chandrashekara

doi:10.5155/eurjchem.3.3.359-362.607

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Published: Sep 30, 2012

DOI: https://doi.org/10.5155/eurjchem.3.3.359-362.607

Keywords:

Ester, Tetrazole, Sulphonation, Benzimidazole, Antioxidant activity, Antimicrobial activity

Section

Short Communication

Issue

Vol. 3 No. 3 (2012): September 2012

Dates

Received 2012-03-07
Accepted 2012-04-11
Published 2012-09-30

Doddarasinakere Kempaiah Ravishankara

Department of Chemistry, Yuvaraja’s College, University of Mysore, Mysore, 570005, India

Paduvalahippe Gowdegowda Chandrashekara

Department of Chemistry, Yuvaraja’s College, University of Mysore, Mysore, 570005, India

Abstract

A series of new benzimidazole derivatives have been synthesized by simple condensation reaction between benzimidazole derivatives and phenyl sulphonyl chloride derivatives. All these compounds were characterized by FT-IR, ¹H NMR, MS and elemental analysis. These compounds were screened for antibacterial and antioxidant activities, respectively. The antibacterial activities were compared with the standard drug such as chlorophenicol and antioxidant activities were compared with the ascorbic acid.

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Ravishankara, D. K.; Chandrashekara, P. G. Synthesis of Some Novel Benzimidazole Derivatives and it’s Biological Evaluation. Eur. J. Chem. 2012, 3, 359-362.

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