European Journal of Chemistry 2012, 3(3), 359-362 | doi: https://doi.org/10.5155/eurjchem.3.3.359-362.607 | Get rights and content






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Synthesis of some novel benzimidazole derivatives and it's biological evaluation


Doddarasinakere Kempaiah Ravishankara (1) , Paduvalahippe Gowdegowda Chandrashekara (2,*)

(1) Department of Chemistry, Yuvaraja’s College, University of Mysore, Mysore, 570005, India
(2) Department of Chemistry, Yuvaraja’s College, University of Mysore, Mysore, 570005, India
(*) Corresponding Author

Received: 07 Mar 2012 | Revised: 04 Apr 2012 | Accepted: 11 Apr 2012 | Published: 30 Sep 2012 | Issue Date: September 2012

Abstract


A series of new benzimidazole derivatives have been synthesized by simple condensation reaction between benzimidazole derivatives and phenyl sulphonyl chloride derivatives. All these compounds were characterized by FT-IR, 1H NMR, MS and elemental analysis. These compounds were screened for antibacterial and antioxidant activities, respectively. The antibacterial activities were compared with the standard drug such as chlorophenicol and antioxidant activities were compared with the ascorbic acid.

3_3_359_362_800


Keywords


Ester; Tetrazole; Sulphonation; Benzimidazole; Antioxidant activity; Antimicrobial activity

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DOI: 10.5155/eurjchem.3.3.359-362.607

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Funding information


Sri Mahadeshwara Government First Grade College, Kollegal, India

Citations

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[1]. Edyta Łukowska-Chojnacka, Patrycja Wińska, Monika Wielechowska, Maria Bretner
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[2]. Haitham Ahmed El-Araby, Abel M. M. A. Ibrahim, Ahmed Hashem Mangood, Adel A.-H. Abdel-Rahman
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[3]. Dnyandev Radhu Gund, Balivada Venkata Satyasai Rao, Pandurang Narayanrao Mandhare, Sanjay Dashrath Vaidya
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[4]. Anuj Kumar, Somesh Banerjee, Partha Roy, S. M. Sondhi, Anuj Sharma
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Molecular Diversity  22(1), 113, 2018
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European Journal of Chemistry  8(2), 149, 2017
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How to cite


Ravishankara, D.; Chandrashekara, P. Eur. J. Chem. 2012, 3(3), 359-362. doi:10.5155/eurjchem.3.3.359-362.607
Ravishankara, D.; Chandrashekara, P. Synthesis of some novel benzimidazole derivatives and it's biological evaluation. Eur. J. Chem. 2012, 3(3), 359-362. doi:10.5155/eurjchem.3.3.359-362.607
Ravishankara, D., & Chandrashekara, P. (2012). Synthesis of some novel benzimidazole derivatives and it's biological evaluation. European Journal of Chemistry, 3(3), 359-362. doi:10.5155/eurjchem.3.3.359-362.607
Ravishankara, Doddarasinakere, & Paduvalahippe Gowdegowda Chandrashekara. "Synthesis of some novel benzimidazole derivatives and it's biological evaluation." European Journal of Chemistry [Online], 3.3 (2012): 359-362. Web. 1 Jun. 2020
Ravishankara, Doddarasinakere, AND Chandrashekara, Paduvalahippe. "Synthesis of some novel benzimidazole derivatives and it's biological evaluation" European Journal of Chemistry [Online], Volume 3 Number 3 (30 September 2012)

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DOI Link: https://doi.org/10.5155/eurjchem.3.3.359-362.607

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