European Journal of Chemistry 2013, 4(1), 25-28. doi:10.5155/eurjchem.4.1.25-28.729

Microwave assisted synthesize of new some benzimidazole derivatives and determination of protonation constant of these compounds in non-aqueous media


Emre Mentese (1) , Fatih Islamoglu (2,*) , Esra Bal (3) , Bahittin Kahveci (4)

(1) Department of Chemistry, Art and Science Faculty, Recep Tayyip Erdoğan University, Rize, 53100, Turkey
(2) Department of Chemistry, Art and Science Faculty, Recep Tayyip Erdoğan University, Rize, 53100, Turkey
(3) Department of Chemistry, Art and Science Faculty, Recep Tayyip Erdoğan University, Rize, 53100, Turkey
(4) Department of Nutrition and Dietetics, Faculty of Health Sciences, Karadeniz Technical University, Trabzon,61080 Turkey
(*) Corresponding Author

Received: 31 Dec 2012, Accepted: 20 Jan 2013, Published: 31 Mar 2013

Abstract


A series of 2-substituted benzimidazole derivatives have been synthesized via microwave mediated process. Different benzimidazole derivatives were titrated with tetrabutylammonium hydroxide in four non-aqueous solvents (isopropyl alcohol, N,N-dimethylformamide,tert-butyl alcohol and acetonitrile), using potentiometric method. The half neutralization potential values and the corresponding pKa values were determined for all cases.

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Keywords


Benzimidazole; Non-aqueous media; Protonation constants; Potentiometric titrations; Iminoester hydrochloride; Microwave assisted synthesis

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DOI: 10.5155/eurjchem.4.1.25-28.729

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[1]. E. Menteşe, I. S. Doğan, B. Kahveci
Green Protocol: Solvent- and Catalyst-Free Synthesis of Benzimidazole Derivatives via Microwave Technique
Chemistry of Heterocyclic Compounds  49(8), 1136, 2013
DOI: 10.1007/s10593-013-1354-6
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How to cite


Mentese, E.; Islamoglu, F.; Bal, E.; Kahveci, B. Eur. J. Chem. 2013, 4(1), 25-28. doi:10.5155/eurjchem.4.1.25-28.729
Mentese, E.; Islamoglu, F.; Bal, E.; Kahveci, B. Microwave assisted synthesize of new some benzimidazole derivatives and determination of protonation constant of these compounds in non-aqueous media. Eur. J. Chem. 2013, 4(1), 25-28. doi:10.5155/eurjchem.4.1.25-28.729
Mentese, E., Islamoglu, F., Bal, E., & Kahveci, B. (2013). Microwave assisted synthesize of new some benzimidazole derivatives and determination of protonation constant of these compounds in non-aqueous media. European Journal of Chemistry, 4(1), 25-28. doi:10.5155/eurjchem.4.1.25-28.729
Mentese, Emre, Fatih Islamoglu, Esra Bal, & Bahittin Kahveci. "Microwave assisted synthesize of new some benzimidazole derivatives and determination of protonation constant of these compounds in non-aqueous media." European Journal of Chemistry [Online], 4.1 (2013): 25-28. Web. 16 Sep. 2019
Mentese, Emre, Islamoglu, Fatih, Bal, Esra, AND Kahveci, Bahittin. "Microwave assisted synthesize of new some benzimidazole derivatives and determination of protonation constant of these compounds in non-aqueous media" European Journal of Chemistry [Online], Volume 4 Number 1 (31 March 2013)

DOI Link: https://doi.org/10.5155/eurjchem.4.1.25-28.729

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