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Microwave assisted synthesize of new some benzimidazole derivatives and determination of protonation constant of these compounds in non-aqueous media
Emre Mentese (1)
, Fatih Islamoglu (2,*) , Esra Bal (3) , Bahittin Kahveci (4) (1) Department of Chemistry, Art and Science Faculty, Recep Tayyip Erdoğan University, Rize, 53100, Turkey
(2) Department of Chemistry, Art and Science Faculty, Recep Tayyip Erdoğan University, Rize, 53100, Turkey
(3) Department of Chemistry, Art and Science Faculty, Recep Tayyip Erdoğan University, Rize, 53100, Turkey
(4) Department of Nutrition and Dietetics, Faculty of Health Sciences, Karadeniz Technical University, Trabzon,61080 Turkey
(*) Corresponding Author
Received: 31 Dec 2012 | Revised: 18 Jan 2013 | Accepted: 20 Jan 2013 | Published: 31 Mar 2013 | Issue Date: March 2013
Abstract
A series of 2-substituted benzimidazole derivatives have been synthesized via microwave mediated process. Different benzimidazole derivatives were titrated with tetrabutylammonium hydroxide in four non-aqueous solvents (isopropyl alcohol, N,N-dimethylformamide,tert-butyl alcohol and acetonitrile), using potentiometric method. The half neutralization potential values and the corresponding pKa values were determined for all cases.
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DOI: 10.5155/eurjchem.4.1.25-28.729
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Citations
[1]. E. Menteşe, I. S. Doğan, B. Kahveci
Green Protocol: Solvent- and Catalyst-Free Synthesis of Benzimidazole Derivatives via Microwave Technique
Chemistry of Heterocyclic Compounds 49(8), 1136, 2013
DOI: 10.1007/s10593-013-1354-6
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DOI Link: https://doi.org/10.5155/eurjchem.4.1.25-28.729
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European Journal of Chemistry 2013, 4(1), 25-28 | doi: https://doi.org/10.5155/eurjchem.4.1.25-28.729 | Get rights and content
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